中医药在急性白血病巩固治疗期的应用研究

目的探讨中医药在急性白血病巩固治疗期的应用研究。方法选取我病区收治的158例急性白血病完全缓解患者按随机化原则分为2组。对照组79例给予单纯西医治疗,观察组79例给予中西医结合治疗,对比两组患者的治疗效果。结果观察组患者治疗中骨髓抑制13.3%、胃肠道反应13.3%、发热20.0%、感染6.7%等毒副作用的发病率明显小于对照组的骨髓抑制26.7%、胃肠道反应33.3%、发热33.3%、感染33.3%,两组比较差异有统计学意义（P〈0.05）。结论急性白血病患者巩固化疗期间加用中医药联合治疗可以有效地缓解化疗药物的毒性作用,提高患者的化疗缓解率、生活质量以及化疗耐受生,具有较好的临床应用意义,值得推广应用。

Application of traditional Chinese medicine in consolidation therapy of acute leukemia

Objective To explore the application of traditional Chinese medicine in consolidation therapy of acute leukemia.Methods 158 cases of patients with complete remission of acute leukemia in our hospital were randomly divided into two groups.79 cases in the control group were treated with simple western medicine while 79 cases in the observation group were treated by combined treatment of traditional Chinese medicine and western medicine. The therapeutic effects of two groups of patients were compared. Results The incidence of bone marrow suppression was 13.3%, gastrointestinal reactions was 13.3%, fever was 20.0%,infections was 6.7% and other side effects of the observation group during the period of conventional chemotherapy and consolidation therapy was significantly less than 26.7% of bone marrow suppression, 33.3% of gastrointestinal reactions, 33.3% of fever and 33.3% of infections of the control group, there was significant difference between two groups（P〈0.05）. Conclusion Application of traditional Chinese medicine in treatment of acute leukemia chemotherapy and consolidation therapy during the conventional chemotherapy and consolidation therapy can effectively alleviate the toxicity of chemotherapy drugs, improve the patient＇s chemotherapy remission rate, quality of life and chemotherapy tolerance, which has a better clinical significances that is worthy of popularization and application.