不同年龄段急性心肌梗死患者血脂水平变化的对比研究

【目的】探讨不同年龄急性心肌梗死（AMI）患者血清中血脂水平。【方法】选择AMI患者102例，按照年龄分为青年组、中年组和老年组，所有患者均在清晨空腹取肘静脉血5mL，采用全自动生化分析仪检测血清中总胆固醇（TC）、甘油三脂（TG）、高密度脂蛋白胆固醇（HDL-C）和低密度脂蛋白胆固醇（LDL-C）水平并比较。【结果】三组患者血清中TC和TG水平比较有统计学差异（P〈0．05），而HDL-C和LDL-C水平无统计学差异（P〉0．05）；中年组和老年组血清中Tc和TG水平明显低于青年组（P〈0．05），老年组患者血清中TC和TG水平显著低于中年组（P〈0．05）；血清中TC和TG与发病年龄呈负相关（P〈0．05）。青年组、中年组和老年组患者TG异常检出率分别为38．46％、20．OO％和12．20％，HDL-C异常检出率分别为11．54％、11．43％和31．71％，三组间TG和HDL-C异常检出率比较有统计学意义（P〈0．05）。【结论】不同年龄组AMI患者血脂水平间存在一定的差异，根据不同情况调脂治疗对预防AMI有重要意义。

Comparative Study of the Changes of Blood Lipids in Patients with Acute Myocardial Infarction at Different Age

Objective]To explore the serum lipid level in patients with acute myocardial infarction（AMI） at different age. ~Methodsl Totally 102 AMI patients were chosen and divided into young group, middle age group and older age group. Venous blood 5ml of all patients was taken at fasting in the morning. Automatic biochemistry analyzer was used to determine serum total cholesterol（TC）, triglyceride（TG）, high density lipoprotein（HDL-C） and low density lipoprotein（LDL-C）, and the results were compared. Results] There were significant differences in serum levels of TC and TG among 3 groups（ P 〈0.05）, while there was no significant difference in HDL-C and LDL-C among 3 groups（ P 〉0.05）. Serum levels of TC and TG in middle age group and older age group were obviously lower than those in young group（ P 〈0.05）, and serum levels of TC and TG in older age group were significantly lower than those in middle age group（ P 〈0.05）. Serum levels of TC and TG are positively correlated with the onset age（ P 〈0.05）. The abnormal detection rates of TG in young group, middle age group and older age group were 38. 46%, 20. 00% and 12. 20% respectively, while those of HDL-C were 11.54%, 11.43 % and 31.71% respectively. There were significant differences in the abnormal detection rates of TG and HDL-C among 3 groups（ P 〈0.05）. Conclusion] Serum lipid level has some differences among AMI patients with different age. Lipid lowering therapy according to different situation has important significance for preventing AMI.