心理干预对多发性硬化伴发抑郁患者的效果观察

【目的】探讨心理干预对改善多发硬化患者抑郁的有效性。【方法】选择2011年10月至2013年2月入住本院神经内科的64例多发硬化伴发抑郁的患者按先后时间段分为对照组32例和干预组32例，干预组在常规护理的基础上，实施心理于预，对照组给予常规护理。两组患者在干预前后分别用抑郁自评量表（SDS）及生活质量量表（SF-36）进行评定。【结果】干预组抑郁得分在干预前后差异有统计学意义（P〈0．05）；对照组无统计学意义（P〉O．05）；干预组干预前后生活质量评定八个维度得分均高于干预前，差异具有统计学意义（P〈O．05）；与对照组相比，生活质量评定八个维度得分均高于对照组（P〈o．05）差异具有统计学意义。【结论】心理干预措施能有效地改善多发性硬化患者的抑郁状态，在提高患者生活质量上起着积极地作用。

Observation on the Efficacy of Psychological Intervention for Patients with Multiple Sclerosis and depression

Objective] To explore the effectiveness of psychological intervention for improving the depres- sion in patients with multiple sclerosis. Methods]A total of 64 patients with multiple sclerosis and depression admitted to our hospital from Oct. 2011 to Feb. 2011 were chosen and randomly divided into intervention group（ n = 32） and control group（ n = 32）. The intervention group was given psychological intervention based on routine care, while the control group was given routine care. Self-reported depression scale（SDS） and quali- ty of life scale（SF-36） were used for the assessment of patients in two groups before and after intervention. Results] There was significant difference in depression scores of intervention group between before and after intervention（ P d0.05）, but there was no significant difference in depression scores of Control group between before and after intervention（ P ~0.05）. In intervention group, the scores of 8 dimensions of quality of life assessment after intervention were higher than those before intervention, and there was significant difference（ P d0.05）. The scores of 8 dimensions of quality of life assessment in intervention group were higher than those in control group, and there was significant difference（ P d0.05）. Conclusion] Psychological intervention can effectively improve depressive state of patients with multiple sclerosis, and plays a positive role in im- proving the quality of life in patients.