内蒙古HIV感染者中新近感染与既往感染比较分析

目的:为了更加充分、准确地了解内蒙古艾滋病疫情特征及现状。方法:收集内蒙古12个盟市2011年第二季度新报告HIV感染病例确证阳性样本,对其进行BED捕获酶联免疫(BED-CEIA)方法检测,以区分HIV感染者中的新近感染与既往感染,比较二者基本信息及实验室检测结果。结果:新近感染的特征是男性所占比例越来越大,年龄更趋年轻化,少数民族明显减少,未婚者比例相对较高,文化水平更高,同性传播为主要传播方式;新近感染者免疫印迹(WB)条带缺失更多,条带p31和gp41仅在新近感染中有缺失;新近感染者CD4+T淋巴细胞数明显高于既往感染者。结论:内蒙古HIV感染呈现新趋势,艾滋病防治工作任重道远。

Comparative analysis of recent infection with HIV and Long-standing infection in inner mongolia

Objective:To get a fuller and more accurate knowledge of current characteristics and situation of the AIDS epidemic in Inner Mongolia.Methods:Collect the newly reported samples of those diagnosed HIV positive carriers in 12 Leagues and cities,Inner Mongolia,in the second quarter of 2011.Test them with BED-CEIA method to distinguish the recent infection sufferers with HIV from the long-standing infection ones.Compare the basic information and laboratory test results of the two groups.Results:Recent infection sufferers are characterized by a growing proportion of men,younger age,and an obvious decrease in ethnic minorities.Besides,relatively unmarried people have a larger proportion among the victims.And they tend to have higher literacy level.Recently,homosexual contact becomes the main transmission.The result shows recent infections suffer more from the lack of Westen Blot(WB) bands,bands p31 and gp41 are only absent in recent infections.At last,recent infections apparently have a larger number of CD4+ T lymphocytes than long-standing infections.Conclusion:HIV infection in Inner Mongolia shows a new trend,and AIDS prevention and control has a long way to go.