BiPAP呼吸机通气治疗OSAHS合并高血压的临床观察

目的探讨应用BiPAP呼吸机通气治疗阻塞性睡眠呼吸暂停综合征（OSAHS）合并高血压的临床疗效。方法对比治疗OSAHS合并高血压患者共64例,观察组32例,对照组32例,同步进行24 h动态血压及多导睡眠仪监测。对照组单用药物治疗,观察组予药物联合无创BiPAP呼吸机持续气道正压通气治疗。结果治疗后观察组与对照组在阻塞性睡眠呼吸暂停综合征临床改善方面具有显著性差异（P〈0.01）;在睡眠呼吸暂停低通气指数（AHI）、最低血氧饱和度方面比较有显著性差异（P〈0.01）;在心率改善方面两组比较差异具有统计学意义（P〈0.05）,但在平均收缩压、平均舒张压改善方面比较,收缩压两组具有显著性差异（P〈0.01）,舒张压具有统计学意义（P〈0.05）。结论 BiPAP呼吸机通气联合药物治疗有助于OSAHS合并高血压患者的血压控制,值得临床推广应用。

Clinical effect observation of BiPAP assisted ventilation in treatment of OSAHS with hypertension

Objective To investigate the clinical efficiency of the face mask bilevel positive airway pressure(BiPAP) assisted ventilation.In the treatment patients of obstructive sleep apnea hypopnea syndrome(OSAHS) with Hypertension.Methods A total of 64 patients with OSAHS with Hypertension confirmed by monitoring of polysomnography monitor were divided into with two groups.Patients in control group(n = 32) were treated by antihypertensive drugs.Patients in treatment group(n = 32) were treated by combination of antihypertensive drugs and BiPAP assisted ventilation.Results Quality of life,heart rate,AHI,Systolic pressure and the bloo Dgas analysis were more significantly improved in the trial group than those in the control groups(P < 0.01).But in the part of heart rate and diastolic pressure,the treatment group groups is much better than the control group(P < 0.05).Conclusion BIPAP assisted ventilation in treatment of obstructive sleep apnea/hypopnea syndrome with Hypertension may gain satisfactory effect.