| Abstract: | A detailed histological review of 196 cases of invasive cutaneous malignant melanoma diagnosed in Western Australia, a high incidence area, during 1975-76 and of 226 cases during the period 1972-76 from the Oxford Region, a low incidence area, was made by one pathologist using the same parameters for each series. Five-year survival rates were analysed with respect to histological features, sex and site, with and without correction for tumour thickness. The results showed higher overall survival rates in Western Australia, with marked differences in prognosis between males and females in the Oxford Region, and between Oxford males and patients of both sexes in Western Australia. These findings were in accord with the corresponding differences in tumour thickness, and they support the theory that survival rates from cutaneous malignant melanoma are higher in areas of high incidence because they are diagnosed and treated earlier. |
