| 足细胞损伤与膜性肾病的研究进展 |
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| 引用本文： | 宋爱凤,杨巧芳,沈敬华. 足细胞损伤与膜性肾病的研究进展[J]. 中国医药科学, 2013, 0(23): 49-51 |
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| 作者姓名： | 宋爱凤 杨巧芳 沈敬华 |
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| 作者单位： | 内蒙古医科大学;内蒙古医科大学中医学院;内蒙古医科大学基础医学院; |
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| 基金项目： | 国家自然基金青年基金资助项目(81102583);内蒙古医科大学博士启动基金(BQ2010YGF) |
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| 摘 要： | 膜性肾病是常见的原发性肾小球疾病，是以肾小球脏层上皮细胞下免疫复合物弥漫性沉积、基底膜增厚伴钉突形成为其病理学特征。其发病机制复杂，近年来，随着对足细胞的一些标志分子的深入研究，证实足细胞的异常与蛋白尿的产生密切相关。在此对足细胞的异常与膜性肾病的发生发展等相关进展作简单综述。
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| 关 键 词： | 足细胞 膜性肾病 蛋白尿 |
Podocyte damage and the research progress of membranous nephropathy |
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| SONG Aifeng,YANG Qiaofang,SHEN Jinghua. Podocyte damage and the research progress of membranous nephropathy[J]. China Medicine and Pharmacy, 2013, 0(23): 49-51 |
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| Authors: | SONG Aifeng YANG Qiaofang SHEN Jinghua |
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| Affiliation: | 1 .Inner Mongolia Medical University,Hohhot 010010,China;2.College of＂ traditional Chinese Medicine,Inner Mongolia Medical University,Hohhot 010010,China; 3.Basic Medical SciencesInner Mongolia Medical University, Hohhot 010010,China) |
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| Abstract: | Membranous nephropathy is a common primary glomerular disease. The pathological features is based on the deposition of immune complexes diffuse glomerular visceral epithelial cells and basement membrane thickening with spikes. Its pathogenesis is complicated. In recent years,the in-depth study of markers of podocytes confirmed that podocytes is closely related to the generation of abnormal proteinuria. This thesis overviewed the progress on podocyte abnormalities of membranous nephropathy development. |
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| Keywords: | Podocyte Membranous nephropathy Proteinuria |
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