丹参和白花丹参叶的化学成分药理研究及临床应用

目的:探讨丹参和白花丹参叶的化学成分药理研究及临床应用,为新药的研制奠定基础。方法:通过参阅大量相关文献,对丹参和白花丹参叶的化学成分、药理研究及临床应用进行分析总结。结果:丹参和白花丹参叶所具有的抗氧化作用均能较好的预防脑梗塞,与根相比叶对脑缺血的保护作用更强,在对心脑血管疾病的防预治疗中被广泛应用;白花丹参叶中的水提物对糖尿病代谢紊乱症状的改善能够起到长期稳定的效果;另外丹参叶在治疗扁平疣、冠心病心绞痛等方面也具有较好的效果。结论:丹参和白花丹参叶均具有稳定的药理作用,但目前在抗氧化和保护脑梗塞的药理研究中仍以白花丹参叶为主,对于丹参叶的药理研究和临床应用则很少。因此对丹参叶主要化学成分进行深入的药理研究是很有必要的。

Pharmacological study on chemical composition and clinical application of Salvia miltiorrhiza and Salvia miltiorrhiza bge.f.alba leaf

Objective：To study the pharmacological effects of chemical composition and clinical application of Salvia miltiorrhiza and Salvia miltiorrhiza bge.f.alba leaf, lay the foundation for the development of new drugs. Method： by referring to a large number of relevant literature, chemical constituents,pharmacological study and clinical application of Salvia miltiorrhiza and Salvia miltiorrhiza bge.f.alba leaf were analyzed. Results：the antioxidant effects of Salvia miltiorrhiza and Salvia miltiorrhiza bge.f.alba leaf has can prevent cerebral infarction better, compared with a protective effect on cerebral ischemia of the leaf is stronger, is widely used in the treatment ofcardiovascular and cerebrovascular disease prevention; Salvia miltiorrhiza bge.f.alba leaf water extract on diabetic metabolic disorder symptoms can playthe long-term stability of the effect of Salvia miltiorrhiza Bunge;in addition alsohas a good effect on the treatment of flat wart, such as coronary heart disease and angina. Conclusion： Salvia miltiorrhiza and Salvia miltiorrhiza bge.f.alba leaf has the pharmacological effects of stable, but thepharmacological study on Antioxidation and protection of cerebral infarction inSalvia miltiorrhiza bge.f.alba leaf, for pharmacological study and clinical application of the leaves of Salvia miltiorrhiza Bge is rarely. Therefore it is necessary to conduct pharmacological study in-depth on chemical components of Salvia miltiorrhiza bunge.