原发性肝癌患者经肝动脉化疗栓塞术后发热与临床疗效分析

目的 探讨原发性肝癌经肝动脉化疗栓塞术（TACE）后发热症状与近期疗效的关系.方法 84例原发性肝癌患者按照TACE术后是否出现发热症状分为无发热组、有发热组两组,比较两组肿瘤在首次介入化疗栓塞术后的治疗效果差异,探讨发热组患者发热时间长短和近期疗效的关系.结果 首次介入术后4～6周行CT和（或）MRI检查,两组肿瘤大小有统计学差异（P=0.031）,且发热组治疗效果优于无发热组.介入治疗后发热4周以上组近期疗效优于发热2周及3周组,发热2周及3周组近期疗效优于发热1周组.结论 肝癌介入治疗后出现发热症状多提示患者肿瘤栓塞近期疗效好,且介入治疗后发热时间和近期疗效呈正相关.

Clinical Analysis of Fever in Patients with Primary Hepatocellular Carcinoma after Transcatheter Arterial Chemoembolization

Objective To investigate the relationship between the fever and the short-term curative effect in patients with primary hepatocellular carcinoma （HCC）after transcatheter arterial chemoembolization（TACE）.Methods According to whether there is a fever after TACE,84 patients with primary liver cancer patients were divided into tow groups：fever group and without fever group.Short-term curative effects at the fourth and sixth week after initial TACE were compared between the two groups,and the relation ship between fever duration and Short-term curative effects was explored.Results Four to six weeks after the initial TACE,CT or MRI scan was performed in all patients.Tumor size of fever group was fignigicantly smaller than without fever group （P =0.031）.Tumor size of fever lasted more than four weeks group was fignigicantly smaller than fever lasted two weeks or three weeks group.Tumor size of fever lasted two weeks or three weeks group was fignigicantly smaller than fever lasted one week group.Conclusion The fever occurred after TACE is a useful suggestive sign,which indicates that a good curative result will be obtained and fever duration after TACE negatively related to short-term efficacy.