天麻素注射液联合注射用血塞通治疗后循环缺血性眩晕临床疗效

目的评价天麻素注射液联合注射用血塞通治疗后循环缺血性眩晕的疗效。方法后循环缺血眩晕患者120例,随机分为天麻素治疗组与对照组各60例,在基础药物治疗的基础上,治疗组采用天麻素注射液0.6g(加入羟乙基淀粉注射液500 mL)联合注射用血塞通0.4g(加入氯化钠注射液250mL),静脉滴注,qd;对照组为羟乙基淀粉注射液及注射用血塞通治疗,剂量同治疗组,疗程均为14d,观察并比较2组对眩晕症状的疗效。结果天麻素治疗组与对照组的临床控制率分别为54%与40%,显效率为30%与17%,有效率为13%与35%,总有效率为97%与92%,2组的总有效率无显著差别(P>0.05),但天麻素治疗组临床控制率及显效率均显著高于对照组(P<0.05)。结论天麻素注射液联合注射用血塞通治疗后循环缺血眩晕的疗效优于单纯应用注射用血塞通。

Therapeutic effect of gastrodin injection combined with sanqi panax notoginseng for injection for patients with vertigo caused by posterior circulation ischemia

AIM To evaluate the efficacy of gastrodin injection combined with sanqi panax notoginseng for injection for the patients with vertigo caused by posterior circulation ischemia(PCI).METHODS One hundred and twenty patients with vertigo caused by PCI were randomly divided into two groups(gastrodin treatment group and control group with 60 patients in each group),and all patients received the same basic treatment.Compared with the patients of control group(hydroxyethyl starch injection 500 mL and sanqi panax notoginseng for injection 0.4 g added into sodium chloride injection 250 mL),the patients of the gastrodin treatment group received gastrodin injection 0.6 g(added into hydroxyethyl starch injection 500 mL) and sanqi panax notoginseng for injection 0.4 g.After a 14-day treatment,the efficacy of the two groups for the treatment of vertigo symptoms were compared.RESULTS There was no statistical difference in the general effect rates of the gastrodin treatment group and the control group(97%vs.92%).The clinical control rate and the significant effect rate of the gastrodin treatment group(54%and 30%) were significantly higher than those of the control group(40%and 17%) with(P<0.05).CONCLUSION The efficacy of gastrodin injection combined with sanqi panax notoginseng for injection maybe better than the application of the latter singlely in the treatment of patients with vertigo caused by PCI.