梅毒荧光吸收试验在早期梅毒和先天性梅毒诊断中的价值

目的]探讨梅毒荧光吸收实验（FTA-ABS）对早期梅毒和先天性梅毒中的诊断价值。方法]利用FTA-ABS、TPHA和RPR同时检测88例梅毒患者、74例非梅毒患者以及82例正常体检者的血清。结果]3种实验的特异性分别为FTA-ABS 100％、TPHA 98．1％、RPR 92、9％，FTA-ABS与TPHA比较无显著性差异（P〉0．05），但高于RPR（P〈0．01）；3种实验的敏感性分别为FTA-ABS 96．6％、TPHA 88.6％、RPR 83．0％，FTA-ABS与TPHA、RPR比较有显著性差异（P〈0．05、P〈0．01）。对一期梅毒的敏感性为FTA-ABS 100％、TPHA 87.1％、RPR 83．9％；对二期梅毒的敏感性均为100％；对三期梅毒的敏感性为FTA-ABS 92.8％、TPHA 100％、RPR 92．8％；对先天性梅毒的敏感性为FTA-ABS 87.5％、TPHA 62．5％、RPR 43．8％，FFA-ABS与TPHA、RPR比较，诊断一期梅毒和先天性梅毒具有显著性差异（P〈0.05、P〈0.01），诊断二期和三期梅毒无显著性差异（P〉0．05）。结论]FTA-ABS是诊断早期梅毒和先天性梅毒的敏感性指标。

Value of FTA - ABS for diagnosis of early syphilis and congenital syphilis

Objective] To study the value of FTA - ABS for diagnosis of early syphilis and congenital syphilis. Methods] The serum samples from 88 patients with syphilis, 74 without and 82 healthy controls were examined by FTA -ABS, TPHA and RPR at the same time. Results] The sensitivity of FTA - ABS for early syphilis and congenital syphilis was significantly higher than that of TPHA and RPR. Conclusion] FTA-ABS is a sensitive method for diagnosis of early syphilis and congenital syphilis.