| ASSAY OF SENSITIVITY OF CANCER CELL TO ANTICANCER DRUG IN GLASS CAPILLARIES |
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| 引用本文： | 贺智敏,魏立勇,彭祥鄂. ASSAY OF SENSITIVITY OF CANCER CELL TO ANTICANCER DRUG IN GLASS CAPILLARIES[J]. 中国癌症研究, 1992, 4(4): 40-45. DOI: 10.1007/BF02996401 |
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| 作者姓名： | 贺智敏 魏立勇 彭祥鄂 |
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| 作者单位： | Research Lab. of Pharmacology，Hunan Medical University，Changsha，Research Lab. of Pharmacology，Hunan Medical University，Changsha，Research Lab. of Pharmacology，Hunan Medical University，Changsha |
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| 摘 要： | A newly established human tumor clonogenecity assay - the glass capillary tube culture technique (CAP assay) to described. With this method, we observed the in vitro anticancer efficiency of several antineoplastics on human solid tumors and acute non-lymphatic leukemia (ANLL) specimen. Comparing with the conventional two-layer agar culture assay (2-LAC assay). The CAP-assay had a higher culture success rate, higher plating efficiency (PE) and shorter experimental period. The preliminary data suggesting and that the CAP assay has the potential to replace the conventional 2- LAC assay for in vitro drug- sensitivity testing and may be applied clinically.
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Assay of sensitivity of cancer cell to anticancer drug in glass capillaries |
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| Zhimin He,Liyong Wei,Xiange Peng. Assay of sensitivity of cancer cell to anticancer drug in glass capillaries[J]. Chinese Journal of Cancer Research, 1992, 4(4): 40-45. DOI: 10.1007/BF02996401 |
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| Authors: | Zhimin He Liyong Wei Xiange Peng |
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| Affiliation: | 1. Research Lab. of Pharmacology, Hunan Medical University, Changsha
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| Abstract: | A newly established human tumor clonogenecity assay - the glass capillary tube culture technique (CAP assay) to described. With this method, we observed the in vitro anticancer efficiency of several antineoplastics on human solid tumors and acute non-lymphatic leukemia (ANLL) specimen. Comparing with the conventional two-layer agar culture assay (2-LAC assay). The CAP-assay had a higher culture success rate, higher plating efficiency (PE) and shorter experimental period. The preliminary data suggesting and that the CAP assay has the potential to replace the conventional 2- LAC assay for in vitro drug- sensitivity testing and may be applied clinically. |
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| Keywords: | glass capillary cell culture drug-sensitivity test. |
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