The effects of the Dietary Approaches to Stop Hypertension (DASH) diet on metabolic risk factors in patients with chronic disease: A systematic review and meta-analysis of randomized controlled trials期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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The effects of the Dietary Approaches to Stop Hypertension (DASH) diet on metabolic risk factors in patients with chronic disease: A systematic review and meta-analysis of randomized controlled trials

Institution:	1. Student Research Committee, Faculty of public health branch, Iran University of Medical Sciences, Tehran, Iran;2. Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran;3. Student Research Committee, Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran;4. Pediatric Gastroenterology, Hepatology and Nutrition Research Center, Research Institute for Children''s Health, Shahid Beheshti University of Medical sciences, Tehran, Iran;5. School of Medicine, University of São Paulo (USP), Ribeirão Preto, Brazil;6. School of Medicine, Federal University of Uberlandia (UFU), Uberlandia, Minas Gerais, Brazil;7. Department of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran;1. Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventative Medicine, Monash University, St Kilda Road, Melbourne, 3004, Australia;2. Nutrition Department, The Alfred Hospital, Commercial Road, Melbourne, 3004, Australia;3. Intensive Care Unit, The Alfred Hospital, Commercial Road, Melbourne, 3004, Australia;4. The Department of Critical Care Medicine, Auckland City Hospital, Park Road, Grafton, Auckland, New Zealand;1. Department of Clinical Pharmacy and Pharmaceutical Care, Medical University of Warsaw, Poland;2. Department of Coronary and Structural Heart Diseases, Cardinal Stefan Wyszynski Institute of Cardiology, Warsaw, Poland;3. Department of Pharmacognosy and Molecular Basis of Phytotherapy, Medical University of Warsaw, Poland;1. Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC;2. Winthrop P Rockefeller Cancer Institute and College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR;3. David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA;4. Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC;5. School of Public Health, Louisiana State University Health Sciences Center, New Orleans, LA;6. Department of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, NY;7. Department of Urology, University of North Carolina at Chapel Hill, Chapel Hill, NC;1. Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Hemmat Highway, 1449614535 Tehran, Iran;2. Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran;3. Department of Nutrition, Faculty of Health, Shahid Sadoughi University of Medical Sciences, 8915173160 Yazd, Iran;1. First Cardiology Clinic, Medical School, National and Kapodistrian University of Athens, Hippokration Hospital, Athens, Greece;2. Department of Cardiology, Helena Venizelou Hospital, Athens, Greece

Abstract:	AimsThe DASH diet was designed for helping control of blood pressure but, fortunately, it can also be prescribed for many other chronic conditions. The current study intended to assess the potential effects of DASH diet on metabolic risk factors in patients with chronic disease.Data synthesisWe carried out a systematic literature search for RCTs from inception until July 2020. A total of 54 clinical trials were included in the final analysis. Compared to control groups, a significant lower effect of the DASH diet was noted for body weight (?1.59 kg; p < 0.001), BMI (?0.64 kg/m²; p < 0.001), and WC (?1.93 cm; p < 0.001) as well as for SBP (?3.94 mmHg; p < 0.001) and DBP (?2.44 mmHg; P < 0.001). The DASH diet significantly decreased TC (?5.12 mg/dl; p = 0.008) and LDL-C levels (?3.53 mg/dl; p = 0.041), but not HDL-C (0.30 mg/dl; p = 0.510), TG (?4.22 mg/dl; p = 0.067), and VLDL-C (?2.16 mg/dl; p = 0.062). No significant effect of the DASH diet was noted for blood glucose (?0.38 mg/dl; p = 0.216), insulin (?0.03 μIU/mL; p = 0.817), HOMA-IR (?0.15; p = 0.132), and CRP (?0.33 mg/l; p = 0.173).ConclusionsThe DASH diet is a feasible approach to weight loss and to control blood pressure and hypercholesterolemia.

Keywords:	Cardiovascular disease DASH diet Hypertension Metabolic syndrome Obesity Weight loss DASH"} {"#name":"keyword" "$":{"id":"kwrd0045"} "$$":[{"#name":"text" "_":"Dietary Approaches to Stop Hypertension SBP"} {"#name":"keyword" "$":{"id":"kwrd0055"} "$$":[{"#name":"text" "_":"systolic blood pressure DBP"} {"#name":"keyword" "$":{"id":"kwrd0065"} "$$":[{"#name":"text" "_":"diastolic blood pressure HDL"} {"#name":"keyword" "$":{"id":"kwrd0075"} "$$":[{"#name":"text" "_":"high-density lipoprotein LDL"} {"#name":"keyword" "$":{"id":"kwrd0085"} "$$":[{"#name":"text" "_":"low-density lipoprotein TC"} {"#name":"keyword" "$":{"id":"kwrd0095"} "$$":[{"#name":"text" "_":"total cholesterol TG"} {"#name":"keyword" "$":{"id":"kwrd0105"} "$$":[{"#name":"text" "_":"triglyceride VLDL-C"} {"#name":"keyword" "$":{"id":"kwrd0115"} "$$":[{"#name":"text" "_":"very low-density lipoprotein BMI"} {"#name":"keyword" "$":{"id":"kwrd0125"} "$$":[{"#name":"text" "_":"body mass index WC"} {"#name":"keyword" "$":{"id":"kwrd0135"} "$$":[{"#name":"text" "_":"waist circumference HOMA-IR"} {"#name":"keyword" "$":{"id":"kwrd0145"} "$$":[{"#name":"text" "_":"homeostatic model assessment for insulin resistance CRP"} {"#name":"keyword" "$":{"id":"kwrd0155"} "$$":[{"#name":"text" "_":"C-reactive protein RCT"} {"#name":"keyword" "$":{"id":"kwrd0165"} "$$":[{"#name":"text" "_":"randomized controlled trial
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