Clinical features of bone and soft tissue tumors of the foot and ankle: Results from a retrospective single-center case-series |
| |
| Institution: | 1. Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, S-1, W-16, Chuo-ku, Sapporo, 060-8543, Hokkaido, Japan;2. Department of Physical Therapy, Sapporo Medical Univ. School of Health Sciences, S-1, W-17, Chuo-ku, Sapporo, 060-8556, Hokkaido, Japan;1. Department of Orthopaedic Surgery, Tohoku University School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi Prefecture, 980-8574, Japan;2. Omagari Orthopaedic Clinic, 11-6-8 Ohanacho, Daisen, Akita Prefecture, 014-0022, Japan;1. Department of Orthopedics and Traumatology, Umraniye Education and Research Hospital, Istanbul, Turkey;2. Department of Orthopedics and Traumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey;3. Department of Orthopedics and Traumatology, ?i?li Etfal Education and Research Hospital, Istanbul, Turkey;4. Department of Orthopedics and Traumatology, Ankara Occupational and Environmental Diseases Hospital, Ankara, Turkey;1. Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kitaku, Okayama City, Okayama, 700-8558, Japan;2. Department of Orthopaedic Surgery, Okayama University Hospital, 2-5-1, Shikata-cho, Kitaku, Okayama City, Okayama, 700-8558, Japan;1. Department of Orthopedic Surgery, Nara Medical University, 840 Shijo-cho, Kashihara City, Nara, 6348522, Japan;2. Department of Orthopedic Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan;3. Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan;4. Department of Orthopedic Surgery, Kansai Medical University, Osaka, Japan;5. Department of Orthopedic Surgery, Tokyo Medical and Dental University, Tokyo, Japan;6. Department of Orthopedic Surgery, Kurume University School of Medicine, Kurume, Japan;7. Department of Orthopedic Surgery, Yamaguchi Rosai Hospital, Yamaguchi, Japan;8. Department of Orthopedic Surgery, Hiroshima City Asa Citizens Hospital, Hiroshima, Japan;9. Department of Orthopedic Surgery, Wakayama Medical University, Wakayama, Japan;10. Department of Orthopedic Surgery, Kochi University, Kochi, Japan;11. Department of Orthopedic Surgery, Kyorin University, Tokyo, Japan;12. Department of Orthopedic Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Japan;13. Department of Orthopedic Surgery, Tokyo Women''s Medical University Medical Center East, Tokyo, Japan;14. Department of Orthopedic Surgery, Yamaguchi University, Yamaguchi, Japan;15. Department of Orthopaedic Surgery, National Defense Medical College, Saitama, Japan;p. Department of Orthopedic Surgery, Kubokawa Hospital, Kochi, Japan;1. Department of Orthopaedics, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan;2. Department of Orthopedic Surgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan;3. Department of Orthopedic Surgery, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan;4. Department of Orthopedic Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo Ward, Chiba, Chiba, 260-0856, Japan;5. Department of Orthopedic Surgery, Shiga University of Medical Science, Tsukinowa-cho, Seta, Otsu, Shiga, 520-2192, Japan;6. Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan;7. Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumaicho, Showa Ward, Nagoya, Aichi, 466-8550, Japan;8. Department of Orthopedic Surgery, Imakiire General Hospital, 4-16 Shimotatsuo, Kagoshima, 892-8502, Japan;9. Department of Orthopedic Surgery, Faculty of Medicine, University of Tsukuba, 2-1-1 Amakubo, Tsukuba, Ibaraki, 305–8576, Japan |
| |
| Abstract: | BackgroundThe malignant potential of the musculoskeletal tumors of the foot and ankle has often been underestimated because of their rarity. The current study reviewed the clinical features of the tumors of the foot and ankle, and evaluated the tumor size via imaging-based analysis to distinguish between benign and malignant lesions.MethodsA retrospective review was performed using the clinical records of all patients with histologically confirmed musculoskeletal tumors of the foot and ankle, treated between 1998 and 2020 at our institution. We examined the distribution of tumors, rate of unplanned excision for primary surgery, and subsequent outcomes. In addition, the tumor size was examined via magnetic resonance imaging, and the cut-off value was determined via receiver operating characteristic (ROC) curve.ResultsA total of 103 bone and soft tissue tumors of the foot and ankle were included, of which 78 were soft tissue tumors and 25 were bone tumors. Of the 14 cases of malignant bone and soft tissue tumors, 6 (42.9%) received unplanned excision in the primary surgery, followed by amputation in 3 cases. Tumor size of malignant soft tissue tumors was significantly larger than that of benign soft tissue tumors (47.6 mm vs. 31.0 mm, respectively, P < .001). However, the difference between benign and malignant bone tumors was not statistically significant with the numbers available. ROC curve determined that the optimum diagnostic cutoff value for soft tissue tumor size was 40 mm, with a high area under the ROC curve 0.816 (95% CI: 0.711–0.921, sensitivity 91.7%, specificity 70.5%)ConclusionsWe highlighted that bone and soft tissue tumors of the foot and ankle were often misdiagnosed and initially inadequately treated. We suggest that a cutoff value of 40 mm may be a useful index for prediction of malignancy in soft tissue tumors of the foot and ankle.Level of evidenceⅢ |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
