| 祛风除痹颗粒制备工艺的实验研究 |
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| 引用本文： | 陈杨芳,王珍,陈师农,田军.祛风除痹颗粒制备工艺的实验研究[J].安徽医药,2009,13(1):19-21. |
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| 作者姓名： | 陈杨芳 王珍 陈师农 田军 |
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| 作者单位： | 安徽中医学院药学院,安徽,合肥,230031;安徽省药品审评认证中心,安徽,合肥,230022;安徽省药物研究所,安徽省中药研究与开发重点实验室,安徽,合肥,230022 |
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| 摘 要： | 目的优选祛风除痹颗粒的最佳制备工艺。方法水提取工艺以干膏得率和芍药苷含量为考察指标，采用正交设计法对其提取工艺条件进行优选。确定了制粒方法。结果水提最佳工艺条件：加8倍量水，煎煮3次，每次1h。以干浸膏法制粒，干膏和辅料比为3：7。结论优选出的制备工艺科学合理，适合工业化生产。
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| 关 键 词： | 祛风除痹颗粒 提取工艺 正交设计 芍药苷 制备工艺 |
Study on the preparation technology of qufengchubi granules |
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| CHEN Yang-fang,WANG Zhen,CHEN Shi-nong,TIAN Jun.Study on the preparation technology of qufengchubi granules[J].Anhui Medical and Pharmaceutical Journal,2009,13(1):19-21. |
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| Authors: | CHEN Yang-fang WANG Zhen CHEN Shi-nong TIAN Jun |
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| Institution: | CHEN Yang-fang1,WANG Zhen2,CHEN Shi-nong3,TIAN Jun3(1.College of Pharmacy,Anhui College of Traditional Chinese Medicine,Hefei Anhui 230031,China,2.Anhui Center for Drug Evaluation & Certification,Hefei,Anhui 230022,3.Anhui Institute of Materia Medica,Anhui Provincial Key Laboratory of R&D of Chinese Medicine,Hefei Anhui 230022,China) |
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| Abstract: | Aim To optimize the preparation technology of qufengchubi granules.Methods With the content of total paeoniflorin presented in the extract and the rate of dried extracts as the indexes for the water extraction process,orthogonal design was used to optimize the conditions for the extraction process.The method of prepared granulation is determined.Results The optimal process of the water extraction for qufengchubi granules was to add 8 times water,decocting 3 times,1 hour for each time.The extracts is granula... |
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| Keywords: | qufengchubi granules extraction technology orthogonal design paeoniflorin preparation technology |
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