Nonoperative management of gastrointestinal malignancies in era of neoadjuvant treatment |
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作者姓名: | Nan Chen Jaffer A Ajani Aiwen Wu |
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作者单位: | 1. Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Gastrointestinal Cancer Center, Peking University Cancer Hospital & Institute;2. Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center |
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基金项目: | supported by National Natural Science Foundation (No. 81773214); |
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摘 要: | Cancers derived from the gastrointestinal(GI) tract are often treated with radical surgery to achieve a cure.However, recent advances in the management of GI cancers involve the use of a combination of neoadjuvant radiation and chemotherapy followed by surgical intervention to achieve improved local control and cure.Interestingly, a small proportion of patients with highly sensitive tumors achieved a pathological complete response(pCR)(no residual tumor cells in the resected specimen) to neoadju...
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