ICAM-1在年龄相关性黄斑变性中的相关研究

年龄相关性黄斑变性（ARMD）是中老年人常见的致盲性眼病，越来越受到人们的关注。现代研究发现：高血脂和动脉粥样硬化（AS）与ARMD有密切的关系，ICAM-1在血脂增高时，在血管内皮细胞的表面表达可能升高，非特异性炎性病变产生。ICAM-1可能通过参与脉络膜慢性非特异性炎症反应而促使干性和湿性ARMD的发生发展。

The Research Related with the Effects of ICAM-1 on the ARMD Pathological Changes

ARMD is the commom ophthalmology disease which often causes blindness.The high incidence of this disease have attracted more attentions.Modern studies discover that hyperlipidemia and AS are closely related with the ARMD.Many researchs have proved that ICAM-1 expressed on the vascular endothelioid celluar may increase when serum lipid level raised and cause non-especial inflammation. ICAM-1 may accelerate progress of the dry and wet ARMD through involved in chronic non-especial inflammation in the chorioidea.