| 血清NO和sIL-2R在肝脏损伤发病机制中作用的探讨 |
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| 引用本文： | 邓剑,向成玉,邓正华.血清NO和sIL-2R在肝脏损伤发病机制中作用的探讨[J].中国临床医学,2004,11(2):253-254. |
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| 作者姓名： | 邓剑 向成玉 邓正华 |
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| 作者单位： | 泸州医学院附属医院检验科,泸州,646000 |
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| 摘 要： | 目的:探讨肝脏疾病患者血清NO和sIL-2R在肝脏损伤发病过程中的作用。方法:分别采用亚硝酸盐还原试验、双抗体夹心Elisa法检测血清NO和sIL-2R。结果:急性肝炎、慢性肝炎、肝硬化和肝癌患者NO、sIL-2R明显高于对照组(P<0.01);各疾病组血清NO与sIL-2R成正相关。结论:NO和sIL-2R在肝脏损伤中起重要作用,检测NO、sIL-2R可以了解肝病患者的免疫功能及肝细胞损伤程度,有助于肝病患者的早期诊断和治疗。
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| 关 键 词： | 血清 NO sIL-2R 肝脏损伤 发病机制 一氧化氮 白细胞介素2受体 |
The Role of Serum NO and sIL-2R in Pathogenesis of Liver Injury |
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| Dengjian Xiang Chengyu Deng Zhenghua.The Role of Serum NO and sIL-2R in Pathogenesis of Liver Injury[J].Chinese Journal Of Clinical Medicine,2004,11(2):253-254. |
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| Authors: | Dengjian Xiang Chengyu Deng Zhenghua |
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| Abstract: | Objective: To investigate the role of serum No and sIL - 2R in pathogenesis mechanism of liver injury. Methods: Serum NO and sIL- 2R were detected by nitrite reduction test and double - sandwich Elisa. Results: The levels in serum NO and sIL - 2R were increased and in patients with acute hepatitis, chronic hepatitis, liver cirrhosis and liver cancer in comparison with normal controls (P<0. 01); There was a positive correlation between NO and sIL- 2R. Conclusion:Serum NO and sIL-2R had important roles in liver injury, it may be study immunology function and level that liver cells were damaged in patients with liver disease to detected serum NO and sIL- 2R, and it is helpful for diagnosing and treating liver disease earlier. |
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| Keywords: | Liver disease Nitric oxide Soluble interleukin - 2 receptor |
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