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A型肉毒杆菌毒素治疗面肌痉挛235例临床研究
引用本文:范文辉,邵淑琴,陈康宁. A型肉毒杆菌毒素治疗面肌痉挛235例临床研究[J]. 中国组织工程研究与临床康复, 2000, 4(7): 1000-1001
作者姓名:范文辉  邵淑琴  陈康宁
作者单位:解放军第三军医大学西南医院重庆 400038
摘    要:目的探讨A型肉毒杆菌毒素(BTXA)治疗面肌痉挛(HFS)的疗效及副作用.方法对235例HFS病人进行面肌多点注射BTXA,对治疗前后的病情分级进行比较,并随访12~36周.结果BTXA治疗的总有效率为98.3%(231/235),无全身反应,半年复发率为60%,药效作用时间平均16周;重复注射同样有效.结论局部注射BTXA是治疗HFS的一种有效手段.

关 键 词:A型肉毒杆菌毒素  面肌痉挛
文章编号:1007-5496(2000)07-1000-02
修稿时间:2000-04-07

Clinical observation of therapeutic effects of botulinum toxin type A on 235 hemifacial spasm patients
FAN Wen-hui SHAO Shu-qin,CHEN Kang-ning.. Clinical observation of therapeutic effects of botulinum toxin type A on 235 hemifacial spasm patients[J]. Journal of Clinical Rehabilitative Tissue Engineering Research, 2000, 4(7): 1000-1001
Authors:FAN Wen-hui SHAO Shu-qin  CHEN Kang-ning.
Abstract:Objective: To explore the therapeutic efficacy of botulinum toxin type A on hemifacial spasm(HFS). Methods: 235 HFS patients were beated with botulinum toxin type A and followed up. Symptomatic alleviations after the injection were graded in comparison with the symptoms at the pretreatment stage. Rusults: The efficient rate was 98. 3% (231 /235 injections) in the 235 cases. but 60% of the patients relapsed about half a year later, the duration of action was average 16 weeks; Conclusions: Botulinum toxin type A is an effective therapy for hemifacial spasm.
Keywords:botulinum toxin type A  hemifacial spasm
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