| 后莫紫檀素、美迪紫檀素对人肝癌细胞抑制作用的研究 |
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| 引用本文： | 李伟东,阚毓铭,洪敏,朱荃.后莫紫檀素、美迪紫檀素对人肝癌细胞抑制作用的研究[J].沈阳药科大学学报,2001,18(3):211-212. |
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| 作者姓名： | 李伟东 阚毓铭 洪敏 朱荃 |
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| 作者单位： | 1. 南京中医药大学科研处
2. 南京中医药大学药学院, |
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| 基金项目： | 江苏省教委自然科学基金资助项目(92089) |
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| 摘 要： | 观察刺果甘草活性成分后莫紫檀素 (homopterocarpin)、美迪紫檀素 (medicarpin)的体外抗癌活性 ,通过人肝癌细胞 (Hep 2 )进行体外实验 ,结果表明它们均有抑制和杀灭人肝癌细胞的作用 ,并且美迪紫檀素的作用强于后莫紫檀素。此 2个单体化合物是刺果甘草的活性成分
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| 关 键 词： | 刺果甘草 后莫紫檀素 美迪紫檀素 人肝癌细胞(Hep-2) |
| 文章编号： | 1006-2858(2001)03-0211-02 |
| 修稿时间： | 2000年10月8日 |
The inhibitory effects of homopterocarpin and medicarpin on human's liver cancer cells in vitro |
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| LI Wei-dong,KAN Yu-ming,HONG Min,ZHU Quan.The inhibitory effects of homopterocarpin and medicarpin on human's liver cancer cells in vitro[J].Journal of Shenyang Pharmaceutical University,2001,18(3):211-212. |
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| Authors: | LI Wei-dong KAN Yu-ming HONG Min ZHU Quan |
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| Institution: | LI Wei dong 1,KAN Yu ming 2,HONG Min 2,ZHU Quan 2 |
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| Abstract: | An observation on the anticancer activity of homopterocarpin and medicarpin in vitro,which was separated from the root of Glycyrrhiza pallidiflora Maxim.. The cell culture test was used in these studies in vitro. The experimental result showed that these two ingredients could inhibite(lower concentration) or kill(higher concentration) human's liver cancer cells under the cultured condition, moreover, the effect of medicarpin was stronger than that of homopterocarpin.These two monomers were active components of Glycyrrhiza pallidiflora Maxim. |
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| Keywords: | Glycyrrhiza pallidiflora Maxim homopterocarpin medicarpin Hep-2 |
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