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| 田口实验设计法优选麻黄提取工艺 | |
| 引用本文： | 李俊各,李建利,王莹,黄娟,刘茜,吕霞,黎婧,赵静. 田口实验设计法优选麻黄提取工艺[J]. 成都中医药大学学报, 2011, 34(1): 73-75 |
| 作者姓名： | 李俊各 李建利 王莹 黄娟 刘茜 吕霞 黎婧 赵静 |
| 作者单位： | 1. 成都中医药大学,药学院,四川,成都,610072 2. 四川省中医药科学院,中医研究所,四川,成都,610031 3. 黑龙江中医药大学,黑龙江,哈尔滨,150040 |
| 摘 要： | 目的:优选麻黄最佳提取工艺.方法:采用田口实验设计法,以乙醇浓度、乙醇用量、提取时间、提取次数为考察因素,以醇提液中盐酸麻黄碱含量为考察指标进行工艺筛选.结果:最佳醇提工艺为6倍量60%乙醇回流提取3次,每次1 h.结论:该工艺稳定可行,简单合理. |
| 关 键 词： | 麻黄 田口实验设计 盐酸麻黄碱 |
Optimize the Extraction Technology of Herba Ephedrae with the Method of Taguchi Experimental Design |
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| Affiliation: | LI Jun-ge1,LI Jian-li2,HUANG Juan1,et al (1.Chengdu University of Traditional Chinese Medicine Pharmacy,Chengdu,Sichuan 610072,2.Traditional Chinese Medicine Academy of Sciences Institute of Sichuan Province,Chengdu,Sichuan 610031) |
| Abstract: | Objective:To optimize the ethanol reflux extraction technology of Herba Ephedrae.Methods:In this research,Taguchi Experimental Design was carried out to investigate the ethanol concentration、the ethanol quantity、extraction time and times、in order to optimized the extract conditions,the study used the content of ephedrine hydrochloride as markers.Results:The optimized ethanol reflux extraction technology was that the 60% ethanol quantity is 6 times as much as the weight of the drugs were added,extracted 3 times,with 1.0 hours for each time.Conclusion:The optimized extraction technology was stable and feasible. |
| Keywords: | Herba Ephedrae Taguchi Experimental Design ephedrine hydrochloride |
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