| 转录因子KLF6研究进展及其在神经损伤再生中的作用 |
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| 引用本文： | 桂婷,丁文龙. 转录因子KLF6研究进展及其在神经损伤再生中的作用[J]. 解剖科学进展, 2012, 18(5): 465-468,472 |
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| 作者姓名： | 桂婷 丁文龙 |
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| 作者单位： | 上海交通大学医学院人体解剖学教研室,上海,200025 |
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| 基金项目： | 上海市科委重点专项,上海市科委国际合作项目,上海市重点学科资助项目,国家985工程创新平台基金 |
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| 摘 要： | Kruppel-like factor6(KLF6)是Krupple样因子家族的一员,其广泛表达于多种组织中,涉及细胞生长与凋亡、肿瘤发生与发展、血管形成及血管损伤后的修复等多种生理病理过程。本文就目前研究中转录因子KLF6的生理和病理学功能,包括神经损伤后再生过程中的作用加以综述。
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| 关 键 词： | 转录因子KLF6 神经损伤再生 细胞生长 肿瘤发生 病理过程 血管损伤 血管形成 再生过程 |
The transcription factor KLF6 and its role in neural regeneration |
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| GUI Ting , DING Wen-long. The transcription factor KLF6 and its role in neural regeneration[J]. Progress of Anatomical Sciences, 2012, 18(5): 465-468,472 |
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| Authors: | GUI Ting DING Wen-long |
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| Affiliation: | (Department of Human Anatomy, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China) |
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| Abstract: | Kruppel-like factor 6 （KLF6） is a member of Kruppel-like factor family, is expressed widely in many tissues, and involved in the regulation of a variety of biological processes, including cell growth, cell apoptosis, tumorigenesis and progression, angiogenesis, vascular injury and repair. An overview will be given here about the function of a transcription factor KLF6 in different physiological or pathological processes, especially its role in the neural regeneration after injury. |
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