慢性荨麻疹与精神焦虑及抑郁症状相关性研究

目的 探讨慢性荨麻疹患者发病与精神焦虑和抑郁症状的相关性。方法 随机选择36例慢性荨麻疹患者为A组,26例皮肤浅部真菌感染患者为B组,健康体检者30例为C组对照。分别用焦虑自评量表(SAS)、汉米顿焦虑量表(HAMA)、抑郁自评量表(SDS)、汉米顿抑郁量表(HAMD)进行症状量化评分检查,将3组的量表得分进行分析比较。结果 根据评分,3组间SAS、HAMA、SDS、HAMD评分差异有显著性(P<0.01),且A组中SAS、HAMA、SDS、HAMD评分均高于C组,差异有显著性(P<0.01)。B组中SAS、HAMA、SDS、HAMD评分与C组相比,差异均无显著性(P>0.05)。3组间用HAMA、HAMD评分结果焦虑及抑郁症状高于分界值(HAMA>14分、HAMD>17分)的发生率差异具有显著性(P<0.01)。A组用HAMA评分焦虑症状高于分界值的发生率(25.0%)较C组(3.3%)高,且差异有显著性(P<0.05);A组用HAMD评分抑郁症状评分高于分界值的发生率(33.3%)较C组(6.7%)高,且差异有显著性(P<0.01);B组与C组用HAMA、HAMD评分焦虑及抑郁症状高于分界值的发生率差异无显著性(P>0.05)。结论 部分慢性荨麻疹患者的发病及迁延不愈可能与精神焦虑及抑郁症状有关。

Study on the Correlation Between Depression, Anxiety and Chronic Urticaria

Objective To investigate the correlation between anxiety,depression and chronic urticaria.Methods Thirty-six patients with chronic urticaria(group A),26patients with superficial fungal infection(group B)and30normal controls(group C)were surveyed using4psychological questionnaires:self-rating anxiety scale(SAS),Hamilton anxiety scale(HAMA),self-rating depression scale(SDS),Hamilton depression scale(HAMD).Results The scores of SAS,HAMA,SDS,HAMD in3groups showed statistically significant differences(P<0.01).The scores of SAS,HAMA,SDS,HAMD in group A were significantly higher(P<0.01)than those of Group C;The scores of SAS,HAMA,SDS,HAMD in group B and group C showed no significant differences(P>0.05).More chronic urticaria patients(25.0%)had anxiety symptoms(HAMA score>14)than those of group C(3.3%,P <0.05).More patients in group A(33.3%)had depression symptoms(HAMD score>17)than group C(6.7%,P<0.01).The differences of anxiety and depression symptoms between group B and group C were not statistically significant(P>0.05).Conclusion The onset and delayed cure of some chronic urticaria may be related to anxiety and depression.