Suppressive mechanism of gastric motility by whole-body vibration |
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Authors: | T. Ishitake Y. Miyazaki H. Ando T. Matoba |
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Affiliation: | (1) Department of Environmental Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011, Japan e-mail: tishitak@med.kurume-u.ac.jp Fax: +81-942-314370, JP |
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Abstract: | Objective: To investigate the mechanism of gastric motility suppression by exposure to whole-body vibration (WBV). Methods: The gastric motility was evaluated by electrogastrography (EGG) under food intake and autonomic nerve blocking agents in ten healthy volunteers. Sinusoidal vertical vibration with a frequency of 4 Hz (1.0 ms−2 rms) was given to the subject for 10 min. Results: The amplitude of EGG wave and the power spectrum corresponding to the slow wave component was remarkably decreased by vibration exposure. Food intake enhanced the gastric motility about 2.5-fold in the power spectral density. During and after vibration exposure, the response mode was similar to those at fasting states. Under the influence of anticholinergic (scopolamine) and alpha-adrenergic blocking agents (prazosin), the power spectra were decreased. A further decrease was observed during vibration exposure. A beta-adrenergic blocking agent (propranolol) led to a marked increase in the amplitude of EGG and its power spectrum. With pretreatment by a beta-adrenergic blocking agent, however, vibration exposure reduced both of them. Conclusions: These results suggest that short-term exposure to WBV can suppress the gastric myoelectric activity, the responses on which may be mediating by neurohumoral effects as well as the mechanical effect of WBV. Received: 7 September 1998 / Accepted: 9 May 1999 |
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Keywords: | Electrogastrography (EGG) Food intake Gastric motility Whole-body vibration |
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