三氧化二砷在肺癌治疗中的研究进展

肺癌是当今发病率及死亡率极高的恶性肿瘤之一,日益威胁着人类的健康。化疗效果不理想,寻求新的化疗药物,或者提高肺癌对化疗药物的敏感性,是目前研究的热点之一。三氧化二砷是中药砒霜的主要成分,主要通过抑制肿瘤细胞的增殖和诱导细胞凋亡发挥抗癌作用,并且具有逆转肿瘤细胞对化疗药物耐药的作用,近来引起了国人对其抗肿瘤作用的重视。因其在祖国医学中应用已久,具有安全、相对低毒的特点,有望成为新的高效、低毒的抗癌药物。

The progress of arsenic trioxide in the treatment of lung cancer

Lung cancer is one of the high morbidity and mortality malignant tumor,a growing threat to human health.Chemotherapy effect is not ideal and seeking new chemotherapeutic agents,or increase in lung cancer chemotherapy sensitivity is currently one of the hot research topics.Arsenic trioxide is Chinese traditional medicine the main component of arsenic,mainly by inhibiting tumor cell proliferation and induction of apoptosis play a role in cancer,and has a reversal of tumor cells to chemotherapeutic drug resistance effect,recently caused a country of its antitumor effect of attention.Because of its long time use in the motherland medicine,its safety,relatively low toxicity characteristics,it is expected to become the new anti-cancer drug with high efficiency and low toxicity.