呼吸重症监护病房呼吸道感染病原菌分布及耐药性分析

目的 为了解我院呼吸重症监护室(RICU)细菌感染分布及耐药情况,方法 对210例入住RICU的下呼吸道感染患者行痰及支气管灌洗液细菌培养及药物敏感性实验.结果 RICU中患者呼吸道感染的主要致病菌为G-细菌(占73.3%),G-细菌以鲍曼不动杆菌、铜绿假单胞菌、大肠埃希菌及洋葱伯克霍尔德菌为主,分别为22.9%,8.6%,6.6%和5.7%;G+细菌以金黄色葡萄球菌为主,占10.5%,真菌占8.6%,以白假丝酵母为主.药敏结果 显示:鲍曼不动杆菌和铜绿假单胞菌对β内酰胺类和碳氢霉烯类抗生素耐药率高.结论 非发酵菌是RICU呼吸道感染的主要致病菌,呼吸道细菌的耐药情况越来越复杂,已成为临床治疗的一个难题.除定期、系统地进行细菌的耐药性检测外,还应规范抗生素的使用,合理使用抗生素以减少耐药菌的产生.

Respiratory intensive care unit of pathogens of respiratory tract infection distribution and drug resistance analysis

Objective To understand my hospital respiratory intensive care unit(RICU) distribution of bacterial infection and drug resistance.Methods 210 cases of patients with lower respiratory tract infection in RICU line of sputum and bronchial lavage fluid bacterial culture and drug sensitivity test.Results The RICU of patients with respiratory tract infection was the main pathogenic bacteria of G-bacteria(73.3%),by Bauman G-bacterium Acinetobacter,Pseudomonas,Escherichia coli and onion Burke Holder bacteria,respectively 22.9%,8.6%,6.6% and 5.7%,G+ bacteria to Staphylococcus aureus,10.5%,fungi accounted for 8.6%,mainly to Candida albicans.Drug sensitivity results show:Bauman Acinetobacter,Pseudomonas aeruginosa toβ-lactam and hydrocarbon of carbapenem antibiotics resistant rate.Conclusion Non fermentative bacteria are main pathogens of RICU respiratory tract infections,bacterial resistance has become more and more complex,the clinical treatment of a difficult problem.In addition to the regular,systematic and bacterial drug resistance testing,should also regulate the use of antibiotics,reasonable use of antibiotics to reduce antibiotic resistance bacteria produce.