| 脑胶质瘤MRI诊断进展——基于脑胶质瘤生理代谢特征的MRI成像 |
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| 引用本文： | 张伟国.脑胶质瘤MRI诊断进展——基于脑胶质瘤生理代谢特征的MRI成像[J].第三军医大学学报,2010,32(20). |
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| 作者姓名： | 张伟国 |
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| 作者单位： | 第三军医大学大坪医院野战外科研究所放射科,重庆,400042 |
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| 基金项目： | 重庆市科技攻关项目(CSTC2007AC5014); 国家重点实验室开放基金(SKLKF200922); 第三军医大学临床科研基金(2009XLC29),第三军医大学回国启动基金(2009XHG14)~~ |
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| 摘 要： | 脑胶质瘤属于神经上皮类肿瘤,是最常见的原发性颅内肿瘤,占脑实质肿瘤的40%～45%.依据病理组织学特征,2000年修订的WHO分级标准将脑内胶质瘤分为低级别(WHO、Ⅱ)和高级别肿瘤(WHO Ⅲ、Ⅳ).低级别胶质瘤占所有胶质瘤的20%～30%,5年生存率接近80%,高级别胶质瘤占脑胶质瘤的50%,其中间变型(WHO Ⅲ)胶质瘤术后生存时间接近2年,胶质母细胞瘤(WHO Ⅳ)的5年生存率仅为5%,多数生存时间少于1年.
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| 关 键 词： | 脑肿瘤 胶质瘤 磁共振成像 磁共振氢质子波谱分析 扩散加权成像 磁共振灌注成像 |
Advanced MR imaging in diagnosis of brain glioma:based on its metabolic and physiological characteristics |
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| Zhang Weiguo.Advanced MR imaging in diagnosis of brain glioma:based on its metabolic and physiological characteristics[J].Acta Academiae Medicinae Militaris Tertiae,2010,32(20). |
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| Authors: | Zhang Weiguo |
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| Institution: | Zhang Weiguo |
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| Abstract: | Glioma is the most common type of primary tumors in the brain,histologically varying from low grade to high grade.Physiological regional heterogeneity also has been well documented in glioma.Hypercellularity,pleomorphism,vascular endothelial proliferation,mitotic activity,and necrosis are important histopathological characteristics,which determine tumor grading and its malignancy.Advanced MR imaging currently provides in vivo physiological and metabolic information including chemical composition,cerebral bl... |
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| Keywords: | brain tumor glioma magnetic resonance imaging proton magnetic resonance spectroscopy diffusion weighted imaging magnetic resonance perfusion imaging |
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