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Phage phi29 protein p56 prevents viral DNA replication impairment caused by uracil excision activity of uracil-DNA glycosylase |
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| Authors: | Serrano-Heras Gemma Bravo Alicia Salas Margarita | |
| Affiliation: | aInstituto de Biología Molecular “Eladio Viñuela,” Centro de Biología Molecular “Severo Ochoa,” Consejo Superior de Investigaciones Científicas-Universidad Autónoma, Nicolás Cabrera 1, Canto Blanco, 28049 Madrid, Spain; and ;bCentro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, Ramiro de Maeztu 9, 28040 Madrid, Spain | |
| Abstract: | Protein p56 encoded by the Bacillus subtilis phage ![[var phi]](corehtml/pmc/pmcents/x03C6.gif "/>29 inhibits host uracil-DNA glycosylase (UDG) activity. In previous studies, we suggested that this inhibition is likely a defense mechanism developed by phage <img src="){kind=small} | |
| Keywords: | φ29 DNA polymerase DNA repair protein-primed replication dUMP incorporation | |
| 本文献已被 PubMed 等数据库收录！ | ||