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| 神经干细胞移植治疗外伤性颅内血肿后遗症20例临床疗效分析 | |
| 引用本文： | 程洪斌,胡韶山,郑永日,李敏,安沂华.神经干细胞移植治疗外伤性颅内血肿后遗症20例临床疗效分析[J].中国康复理论与实践,2007,13(5):454-455. |
| 作者姓名： | 程洪斌 胡韶山 郑永日 李敏 安沂华 |
| 作者单位： | 1. 哈尔滨医科大学第二临床医学院神经外科,黑龙江哈尔滨市,150086;武警总医院神经干细胞移植科,北京市,100039 2. 哈尔滨医科大学第二临床医学院神经外科,黑龙江哈尔滨市,150086 3. 武警总医院神经干细胞移植科,北京市,100039 4. 武警总医院神经干细胞移植科,北京市,100039;首都医科大学附属北京天坛医院,北京市神经外科研究所神经干细胞室,北京市,100050 |
| 基金项目： | 国家自然科学基金;北京市科技新星计划项目 |
| 摘 要： | 目的探讨应用神经干细胞移植治疗外伤性颅内血肿后遗症的临床疗效。方法对20例外伤性颅内血肿后遗症患者行腰椎穿刺蛛网膜下腔注入神经干细胞,并于第1次术前和第4次术后半年进行功能独立性评定（FIM）。结果患者自我料理、括约肌控制、活动和转移、运动、交流、社会认知都有明显改善（P〈0.01）。结论神经干细胞移植可以改善外伤性颅内血肿患者损伤的症状和体征,提高患者生活质量。 |
| 关 键 词： | 神经干细胞 创伤性脑损伤 功能独立性评定 脑出血 |
| 文章编号： | 1006-9771（2007）05-0454-02 |
| 收稿时间： | 2006-10-10 |
| 修稿时间： | 2007-02-01 |
Effect of Neural Stem Cells Transplantation on Sequela after Traumatic Intracranial Hematoma |
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| CHENG Hong-bin, HU Shao-shan, ZHENG Yong-ri ,et al..Effect of Neural Stem Cells Transplantation on Sequela after Traumatic Intracranial Hematoma[J].Chinese Journal of Rehabilitation Theory and Practice,2007,13(5):454-455. | |
| Authors: | CHENG Hong-bin HU Shao-shan ZHENG Yong-ri |
| Institution: | CHENG Hong-bin, HU Shao-shan, ZHENG Yong-ri , et al. |
| Abstract: | Objective To investigate the curative effect of neural stem cells (NSCs) transplantation on sequela after traumatic intracranial hematoma. Methods 20 patients with sequela after traumatic intracranial hematoma were treated with NSCs transplantation. Cells were engrafted into subarachnoid cavity via lumbar puncture. They were assessed with Functional Independence Measure (FIM) before and half a year after the transplantation. Results The FIM scores were significantly increased after the transplantation (P<0.01).Conclusion NSCs transplantation could promote functional recovery and improve the living quality of patients with sequela after traumatic intracranial hematoma in the aspects of self-care, sphincter control, mobility, locomotion, communication and social adjustment/cooperation. |
| Keywords: | neural stem cell trauma brain iniury Functional Independence Measure brain hemorrhage |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |