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Postvaccination Bullous Pemphigoid in Infancy: Report of Three New Cases and Literature Review
Authors:Sonia de la Fuente M.D.  Ángela Hernández‐Martín M.D.  Raúl de Lucas M.D.  MªAntonia González‐Enseñat M.D.  Asunción Vicente M.D.  Isabel Colmenero M.D.  María González‐Beato M.D.  Mariona Suñol M.D.  Antonio Torrelo M.D.
Affiliation:1. Department of Dermatology, Hospital Infantil Ni?o Jesús, , Madrid, Spain;2. Department of Dermatology, Hospital La Paz, , Madrid, Spain;3. Department of Dermatology, Hospital San Joan de Deu, , Barcelona, Spain;4. Department of Pathology, Hospital Infantil Ni?o Jesús, , Madrid, Spain;5. Department of Pathology, Hospital La Paz, , Madrid, Spain;6. Department of Pathology, Hospital San Joan de Deu, , Barcelona, Spain
Abstract:Bullous pemphigoid (BP) is an acquired autoimmune blistering disorder of unknown etiology uncommon in childhood. Unlike adult BP, infantile BP shows acral distribution and resolves rapidly with systemic steroids. We report three infants with infantile BP presenting shortly after vaccination for diphtheria, pertussis, tetanus, poliomyelitis, hepatitis B, Haemophilus influenzae B, and meningococcus C. Our cases further reinforce the causal association between childhood BP and vaccination.
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