早产儿视网膜病变治疗研究新进展

早产儿视网膜病变(retinopathy of prematurity,ROP)是早产儿和低体重儿发生的一种视网膜血管增生性病变,近年来随着早产儿的存活率不断提高,ROP的发生率也明显增加。以往ROP的治疗主要是在阈值期或阈值后期,给予视网膜激光及手术治疗为主,同时给予机体全身应用激素药物,因治疗时机晚,且手术风险大、并发症多,治疗效果很不理想。寻找一种在病变发生早期应用,且操作简单的安全、有效的治疗方法,已成为研究者的共识。我们就目前治疗ROP的新进展进行综述。

New progress on the treatment of retinopathy of prematurity

·Retinopathy of prematurity(ROP)is retinal vascular proliferative lesion occurred in prematurity and low birth weight infants.With the rising of the survival rate of premature children in recent years,the incidence of ROP has increased significantly.ROP treatment in the threshold or late threshold period is mainly the retinal laser and surgical treatment,while giving the body systemic hormone drugs.Due to the late timing of treatment,high surgical risks and many complications,the treatment effect is not ideal.To explore a simple,safe and effective treatment method has become the consensus of researchers in the early lesions stage.We reviewed the new progress on the current treatment of ROP.·