| eNOS和P450在大鼠性成熟期睾丸的表达及意义 |
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| 引用本文： | 任亚萍,孙莉,邵晓云,陈筠,熊彬,农林琳. eNOS和P450在大鼠性成熟期睾丸的表达及意义[J]. 中华男科学杂志, 2009, 0(10): 911-914 |
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| 作者姓名： | 任亚萍 孙莉 邵晓云 陈筠 熊彬 农林琳 |
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| 作者单位： | 桂林医学院组胚教研室; |
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| 基金项目： | 2005-2010广西学位授权点学科建设和研究生教育发展规划经费(桂学位200420号文件)~~ |
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| 摘 要： | 目的:探讨内皮型一氧化氮合酶(eNOS)和细胞色素P450(芳香化酶)在雄性SD大鼠性成熟期睾丸中的表达及意义。方法:选取出生后5周、7周和10周的雄性SD大鼠各6只,左侧睾丸行石蜡切片,运用免疫组化ABC法观察eNOS和P450在雄性SD大鼠性成熟期睾丸中的表达变化情况。结果:出生后5周、7周和10周,睾丸间质细胞胞质eNOS和P450免疫反应阳性,阳性程度皆为(+++)、(+)和(++);精母细胞胞质eNOS和P450免疫反应阳性表达,但细胞数量较少,且无规律可循。结论:在性成熟期雄性SD大鼠的睾丸间质细胞中,随着性成熟发育的进展过程,eNOS和P450的表达强弱有所不同,且两者具有关联性。
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| 关 键 词： | 内皮型一氧化氮合酶 睾丸 SD大鼠 性成熟 |
Expressions of eNOS and Cytochrome P450 in the Testis of Sexually Mature SD Rats and Their Significance |
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| REN Ya-ping,SUN Li,SHAO Xiao-yun,CHEN Jun,XIONG Bin,NONG Lin-lin. Expressions of eNOS and Cytochrome P450 in the Testis of Sexually Mature SD Rats and Their Significance[J]. National journal of andrology, 2009, 0(10): 911-914 |
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| Authors: | REN Ya-ping SUN Li SHAO Xiao-yun CHEN Jun XIONG Bin NONG Lin-lin |
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| Affiliation: | REN Ya-ping,SUN Li,SHAO Xiao-yun,CHEN Jun,XIONG Bin,NONG Lin-linDepartment of Histology , Embryology,Guilin Medical College,Guilin,Guangxi 541004,China |
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| Abstract: | Objective: To explore the expressions of endothelial nitric oxide synthase(eNOS) and cytochrome P450(aromatase) in the testis of sexually mature male SD rats and their significance.Methods: Eighteen male SD rats,6 five-week,6 seven-week and 6 ten-week old,were selected for this study.Paraffin sections of the left testis were made and the expressions of eNOS and P450 observed by the immunohistochemical ABC method.Results: Positive expressions of eNOS and P450 were found to be +++,+ and ++ in the Leydig cells... |
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| Keywords: | eNOS testis SD rat sexual maturity |
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