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Clustering of glycoprotein VI (GPVI) dimers upon adhesion to collagen as a mechanism to regulate GPVI signaling in platelets
Authors:N. S. Poulter  A. Y. Pollitt  D. M. Owen  E. E. Gardiner  R. K. Andrews  H. Shimizu  D. Ishikawa  D. Bihan  R. W. Farndale  M. Moroi  S. P. Watson  S. M. Jung
Affiliation:1. Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK;2. Centre for Membrane Proteins and Receptors (COMPARE), College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK;3. Department of Physics and Randall Division of Cell and Molecular Biophysics, King's College London, London, UK;4. Department of Cancer Biology and Therapeutics, John Curtin School of Medical Research, Australian National University, Canberra, ACT, Australia;5. Australian Centre for Blood Diseases, Monash University, Melbourne, Victoria, Australia;6. Research Department, Chemo‐Sero‐Therapeutic Research Institute, Kaketsuken, Kumamoto, Japan;7. Department of Biochemistry, University of Cambridge, Cambridge, UK
Abstract:
Keywords:glycoprotein  platelet activation  platelet adhesiveness  platelet membrane glycoproteins  receptors, collagen
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