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The structural basis for the functional comparability of factor VIII and the long‐acting variant recombinant factor VIII Fc fusion protein |
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| Authors: | N. C. Leksa P.‐L. Chiu G. M. Bou‐Assaf C. Quan Z. Liu A. B. Goodman M. G. Chambers S. E. Tsutakawa M. Hammel R. T. Peters T. Walz J. D. Kulman |
| Affiliation: | 1. Biogen, Cambridge, MA, USA;2. Department of Cell Biology, Harvard Medical School, Boston, MA, USA;3. Molecular Biophysics & Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, CA, USA;4. Laboratory of Molecular Electron Microscopy, Rockefeller University, New York, NY, USA |
| Abstract: | |
| Keywords: | B‐domain‐deleted factor VIII bleeding factor VIII hemophilia A rFVIIIFc protein |