长三角地区常规体检人群睑结膜结石流行状况和病理探讨

目的调查长三角地区眼睑结膜结石的流行状况。方法连续3617例常规眼科体检者,男2154人,女1463人,年龄（38.2±11.6）岁。翻开被检查者上下眼睑,裂隙灯下检查,对结石阳性者进行裂隙灯下照相保存,按年龄和性别分组,观察结石所处的部位、数量、形状、质地、大小、充血等发病情况。结果结膜结石患病率为8.76%（317人）,有症状的仅占3.8%（12/317）。上睑多于下睑（χ2=175.01,P=0.000〈0.05）,右眼结石多于左眼（χ2=9.788,P=0.002〈0.05）,50岁以上结石患病率比50岁以下高（χ2=29.812,P=0.000〈0.05）,具有统计学意义,男女结石患病率区别无统计学意义（χ2=0.256,P=0.613〉0.05）。软胶样结石（79.5%）比质硬结石更为多见,结石分布多见于上穹隆部/副泪腺区（66.9%）和上外侧/泪腺区（40.4%）。结膜结石患者结膜充血发生率较高（相对危险度RR=1.44〉1）,结论长三角地区结膜结石流行病学数据模型得以建立,结膜结石具有多种病因病理而致临床表现多样。

The prevalence and pathological charactersof conjunctival concretions in the Yangtze River Delta region

Objective To survey the prevalence of conjunctival concretions in the Yangtze River Delta region,and to characterize the pathological presentations of conjunctival concretions in the region. Methods Both eyes of 3617 patients coming for routine ophthalmiccheckups were examined under slip lamps for conjunctival concretions. Observed conjunctival concretions were photographed and their number,positions,shapes,hardness and conjunctival hyperemia were recorded. These data were analyzed for different genders and ages. Results Although the prevalence of conjunctival concretion was 8. 76%（317 /3617）,it caused symptomsin only 3. 8%（12 /317） of patients. Superficial deposits were more common than（χ2= 175. 01,P 〈0. 01）,andwerefound in right eyesmore often than in left eyes（χ2= 9. 788,P〈 0. 01）.Patients over 50 years old were more susceptible to conjunctival concretions（χ2= 29. 812,P 〈0. 01）. There was no difference between male and female（ χ2= 0. 256,P = 0. 613）. Gelatinous deposit（79. 5%） was thedominant type and was found to distribute mainly in upper fornix（66. 9%） orupper lateral palpebral conjunctiva（40. 4%）. Conjunctival hyperemiawas common in patients with concretions and the RR（ Relative Risk） was 1. 44. Conclusion We have estimated the prevalence of conjunctival deposits in random cohort of patients in Yangtze River Delta region. Conjunctival concretions have various clinical manifestations and pathological characters.