Nuclear ploidy as an indicator of malignancy of intraductal pancreatic papillary mucinous tumors |
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| Authors: | Dubova E A Podgornova M N Shchyogolev A I |
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| Affiliation: | (1) Department of Radiation Oncology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA; |
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| Abstract: | Comparative morphometric and densitometric studies of cell nuclei in endocrine tumors of various differentiation degree and endocrinocytes of Langerhans islet in the adjacent pancreatic tissue were carried out. Index of proliferative activity, aneuploidy coefficient, and histogram of nuclear DNA content are recommended as additional criteria for the diagnosis of endocrine tumor malignancy. |
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