超声引导经皮双极射频消融治疗肝癌的局部疗效观察

目的观察超声引导经皮双极射频消融治疗肝癌的局部疗效。方法选取我院2012年5月~2013年10月收治、以治愈性治疗为目的的24例肝癌患者32个病灶,对所有患者均采取超声引导下经皮双极射频消融进行治疗,术后1个月观察患者影像学(超声造影、增强CT或增强MRI)检查结果,以评价局部疗效,以后每3个月随访一次,以观察患者复发情况。结果病灶完全消融(CA)率96.9%(31/32),其中最大径3cm病灶CA率为100%(27/27),最大径≥3cm病灶CA率为80%(4/5);原发性肝癌完全CA率95.7%(22/23),转移性肝癌CA率100%(9/9)。所有患者均未出现严重并发症及与手术相关的死亡。随访2~19个月,局部复发率为6.3%(2/32)远处复发率为33.3%(8/24)。结论超声引导下经皮双极射频消融治疗肝癌安全可靠、局部疗效确切,对小肝癌尤其明显。

Local therapeutic efficacy of ultrasound-guided percutaneous bipolar radiofrequency ablation for liver cancer

Objective To observe the local therapeutic efficacy of ultrasound-guided percutaneous bipolar radiofrequency ablation for liver cancer.Methods 24 patients with 32 liver tumor nodules who were referred to our hospital from May,2012 to October,2013.All patients were treated with ultrasound-guided percutaneous bipolar radiofrequency ablation with curative intention. We Observed the local therapeutic efficacy of all patients within one month after the treatment.The imageological examination （Contrast-enhanced ultrasound,contrast-enhanced Computed Tomography or contrast-enhanced magnetic Resonance Imaging） were used to decide the local therapeutic efficacy.We obeserved the recurrence of the tumors through the follow-up of every three months.Results Complete ablation（CA）was achieved in 96.9%（31/32）of tumor nodules.The CA rate was remarkably higher in nodules ≤3 cm（100%,27/27）than that in nodules 〉3 cm（80%,4/5）（P〈0.05）.CA rate was 95.7%（22/23）for primary liver cancers and 100%（9/9）for metastatic liver cancers.There was no mortality associated with bipolar radiofrequency ablation. Patients were followed-up from 2-19 months.The local recurrence rates were 6.3%（2/32）and the distant recurrence rates were 33.3%（8/24）.Conclusion Ultrasound-guided percutaneous bipolar radiofrequency ablation for liver cancer is a safe and effective method, especially for small liver cancers.