尿胰蛋白酶原—2测定对急性胰腺炎的早期诊断价值

目的 探讨尿胰蛋白酶原－2测定在急腹症中筛选急性胰腺炎的价值。方法 对346例连续就诊的急腹症病人同时测定尿胰蛋白酶原－2及血、尿淀粉酶。结果 41例急性胰腺炎中有38例尿胰蛋白酶原－2阳性，敏感性为92．7％，305例非胰腺炎的急腹症病人有15例假阳性，特异性为95．1％。5例重症急性胰腺炎中尿胰蛋白酶原－2全部阳性。结论 尿胰蛋白酶原－2是急腹症病人筛选急性胰腺炎快而简便的方法，具有较高的特异性和敏感性。

Measurement of urinary trypsinogen-2 as a screening test for acute pancreatitis in patients with acute abdomen

Objective To evaluate the value of urinary trypsinogen-2 test for screening acute pancreatitis in patients with acute abdomen. Methods Urinary trypsinogen-2 as well as serumal and urinary amylase were assayed in 346 patients with acute abdomen. Results The diagnosis of acute pancreatitis was established in 41 patients. Among them,38 cases with positive urinary trypsinogen-2 were found, the sensitivity was 92.7%. 15 cases with false positive were found in 305 cases of non-pancreatitis patients,the specificity was 95.1%. All of the five patients with severe acute pancreatitis were positives. Conclusion Urinary trypsinogen-2 test is an easy and rapid diagnostic method with high sensitivity and specificity for screening acute pancreatitis in patients with acute abdomen.