在园儿童携带EV71和CoxA16的调查研究

目的了解手足口病的流行期和非流行期在园儿童肠道病毒EV71与柯萨奇病毒CoxA16携带水平。方法采用随机整体抽样方法．对3家幼儿园5岁以下儿童采集咽拭子，进行实时荧光PCR检测。结果非流行期176名在园儿童有4名CoxA16阳性，阳性率为2．3％，2名EV71阳性，阳性率为1．1％。流行期216名在园儿童有7名CoxA16阳性，阳性率为3．2％，5名EV71阳性，阳性率为2．3％。结论深圳某地手足口病在流行期和非流行期，在园儿童病原体携带无显著差异；应采取措施加强对手足口病的预防和控制工作。

Investigation and research on the carrying rate of EV71 and CoxA16 of kindergarten children

Objective To understand the carrying rate of kindergarten children of enterovirus EV71 and Coxsackie virus CoxA16 in epidemic period and non-epidemic period. Methods With overall random sampling method, the throat swab samples collected from three kindergartens children under 5 and detected by real-time fluorescence PCR. Results In non-epidemic period , 176 children had 4 ease of CoxAl6,the positive rate was 2.3% , 2 case of EV71, the positive rate was 1.1%; in epidemic period 216 children had 7 CoxA16, the positive rate was 3.2%, 5 EV71 positive, the positive rate was 2.3%. Conclusion In the epidemic period and non-epidemic period of hand-foot-mouth disease, the carryingrate of pathogens in kindergarten children was no significant difference; The measures should be taken to prevent and control the hand,foot and mouth disease.