| 肝癌高发区不同人群乙肝及丙肝病毒标志物阳性率的变化 |
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| 引用本文： | 朱源荣,陆建华,王金兵,陆玲玲,陈建国.肝癌高发区不同人群乙肝及丙肝病毒标志物阳性率的变化[J].中国肿瘤,2011,20(6):409-412. |
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| 作者姓名： | 朱源荣 陆建华 王金兵 陆玲玲 陈建国 |
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| 作者单位： | 启东肝癌防治研究所,江苏启东,226200 |
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| 基金项目： | 江苏省卫生科研基金资助项目(H200958)(H201053) |
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| 摘 要： | 目的]调查启东肝癌高发区不同人群乙型肝炎病毒（HBV）及丙型肝炎病毒（HCV）标志物的阳性率,并观察其变化趋势。方法]收集启东肝癌患者、肝癌高发家族成员、HBsAg携带者、急性肝炎患者和自然人群共计1029例血清,分别做HBsAg、抗-HCV、AFP、ALT检测。结果]抗-HCV阳性率自然人群与肝癌患者分别为1.00%与0.40%,自然人群HBsAg阳性率为8.00%,肝癌患者AFP阳性率为66.67%,均较历史资料有明显的下降;肝癌患者HB-sAg和ALT阳性率无明显变化;25岁以上自然人群ALT阳性率为7.50%;肝癌高发家族成员HBsAg阳性率为28.24%,与急性肝炎患者的28.99%基本相仿。结论]乙肝和丙肝多项血清学指标阳性率的明显下降,可能预示着当地肝癌发病因素的改变或控制。
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| 关 键 词： | 肝癌 乙肝病毒 丙肝病毒 甲胎蛋白 高发区 江苏 |
Changes of HBV and HCV in Various Populations from High-risk Area of Liver Cancer |
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| ZHU Yuan-rong,LU Jian-hua,WANG Jin-bing,et al..Changes of HBV and HCV in Various Populations from High-risk Area of Liver Cancer[J].Bulletin of Chinese Cancer,2011,20(6):409-412. |
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| Authors: | ZHU Yuan-rong LU Jian-hua WANG Jin-bing |
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| Institution: | ZHU Yuan-rong,LU Jian-hua,WANG Jin-bing,et al.(Qidong Liver Cancer Institute,Qidong 226200,China) |
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| Abstract: | Purpose] To investigate the trends on positive rates of hepatitis B virus (HBV) and hepatitis C virus (HCV) in various populations in Qidong.Methods] One thousand and twenty-nine serum samples were collected from those with liver cancer,the members of families at risk with liver cancer,the carriers of hepatitis B surface antigen (HBsAg),the patients with acute hepatitis and the general population,to test HBV markers,anti-HCV antibody,alpha-fetoprotein (AFP) and alanine transaminase (ALT).Results] The pos... |
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| Keywords: | liver cancer HBV HCV AFP high incidence area Jiangsu |
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