| HLA单倍体异基因造血干细胞移植治疗重症再生障碍性贫血的护理 |
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| 引用本文： | 张莹,王静.HLA单倍体异基因造血干细胞移植治疗重症再生障碍性贫血的护理[J].军医进修学院学报,2012,33(2):169-170. |
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| 作者姓名： | 张莹 王静 |
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| 作者单位： | 解放军总医院第一附属医院 血液科,北京,100048 |
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| 摘 要： | 目的 探讨HLA单倍体异基因造血干细胞移植治疗重症再障性贫血患者的护理.方法 针对移植患者的干细胞回输、移植后移植物抗宿主病(GVHD)及相关并发症进行护理.结果 移植过程顺利,白细胞植入中位时间13d,血小板植入中位时间14d.4例患者中有2例出现皮肤急性GVHD,1例出现肠道急性GVHD,1例出现出血性膀胱炎.结论 移植过程中及时发现并正确处理GVHD及感染、口腔黏膜炎、出血性膀胱炎是提高移植成功率的关键因素.
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| 关 键 词： | HLA单倍体 异基因移植 再生障碍性贫血 护理 |
Nursing for patients with severe aplastic anemia after HLA haploid allo-hematopoietic stem cell transplantation |
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| ZHANG Ying
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WANG Jing.Nursing for patients with severe aplastic anemia after HLA haploid allo-hematopoietic stem cell transplantation[J].Academic Journal of Pla Postgraduate Medical School,2012,33(2):169-170. |
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| Authors: | ZHANG Ying WANG Jing |
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| Institution: | Section of Hematology,The First Affiliated Hospital,Chinese PLA General Hospital,Beijing 100048,China |
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| Abstract: | Objective To study the nursing for patients with severe aplastic anemia after HLA haploid allo-hematopoietic stem cell transplantation(allo-HSCT).Methods Patients with severe aplastic anemia were nursed according to re-transfusion of stem cells,graft-versus-host disease(GVHD) and complications after allo-HSCT.Results The allo-HSCT was successful.The median time of white blood cell and platelet transplantation was 13 and 14 days,respectively.Skin acute GVHD,intestinal acute GVHD,and hemorrhagic cystitis occurred in 2,1 and 1 out of the 4 patients.Conclusion Prompt finding and correct management of GVHD,infection,oral mucositis,and hemorrhagic cystitis during allo-HSCT are the key factors for the successful allo-HSCT. |
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| Keywords: | HLA haploidy allogenenic transplantation aplastic anemia nursing care |
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