| 蝮蛇抗栓酶对高粘血症病人的血液流变学和甲襞微循环的影响 |
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| 引用本文： | 苏林青,丁世芳,马大波,王淑君,孙洁,田眼亮.蝮蛇抗栓酶对高粘血症病人的血液流变学和甲襞微循环的影响[J].中国新药与临床杂志,1995(2). |
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| 作者姓名： | 苏林青 丁世芳 马大波 王淑君 孙洁 田眼亮 |
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| 作者单位： | 中国人民解放军广州军区武汉总医院 |
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| 摘 要： | ２１０例高粘血症病人（男性１４６例，女性６４例；年龄６２±ｓ８ａ）．经用蝮蛇抗栓酶１．０Ｕ加１０％葡萄糖液２５０ｍＬ，静脉滴注。１次／ｄ，１５ｄ为一个疗程。观察治疗前后全部病人的血液流变学和６０例甲襞微循环的变化，结果：治疗后凝血因子Ⅰ、全血比粘度、血浆比粘度均显著下降（Ｐ＜０．０１）。甲襞微循环也显示：淤血及红细胞聚集缓解，血流态异常好转，血流速加快，微循环明显改善。
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| 关 键 词： | 蝮蛇抗栓梅 蛇毒类：血液粘度 流变学 微循环 |
Influences of Fu-she-kang-shuan-mei on hemorheology and hyponychial microcirculation of patients with hyperhemoviscositosis |
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| SU Lin-Qing, DING Shi-Fang,MA Da-Bo,WANG Shu-Jun,SUN Jie,TIAN Yan-Liang.Influences of Fu-she-kang-shuan-mei on hemorheology and hyponychial microcirculation of patients with hyperhemoviscositosis[J].Chinese Journal of New Drugs and Clinical Remedies,1995(2). |
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| Authors: | SU Lin-Qing DING Shi-Fang MA Da-Bo WANG Shu-Jun SUN Jie TIAN Yan-Liang |
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| Abstract: | Patients(M146,F64;age 62± s 8 a) with hyperhemoviscositosis were treated with Fu-she-kang-shuan-mei 1 U diluted in 10% glucose 250 mL,iv,gtt,qd,for 15 d.Before and after treatment the hemorheology of all patients and hyponychial microcirculation of 60 patients were observed.The results showed that after the usage of Fu-she-kang-shuan-mei fibrinogen level decreased remarkably(t test,P<0.01).Whole blood viscosity,high shear rate,low shear rate and serum relative viscosity lowered(P<0.01).Hyponychial microcirculation also presented that passive congestion and red blood cell aggregation were alleviated, the blood flow state abnormality was improved,blood velocity increased.The hyponychial microcirculation became into better condition. |
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| Keywords: | Fu-she-kang-shuan-mei snake venoms blood viscosity rheology microcirculation |
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