Immunoglobulin Analysis in Clinical Diagnosis

Serum protein electrophoresis, ultracentrifugation, immunoelectrophoresis and immunodiffusion are the four methods commonly used for quantitation of immunoglobulins. Deficiencies of one or more of the five known types of immunoglobulins are demonstrable in a diverse group of diseases making up the antibody deficiency syndromes, while increased amounts of immunoglobulin may be found in various other diseases.