| 甘草汤对大鼠心肌缺血再灌注损伤的影响 |
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| 引用本文： | 李美平,何承敏,胡继鹰,尤行宏,胡平. 甘草汤对大鼠心肌缺血再灌注损伤的影响[J]. 湖北中医药大学学报, 2011, 13(1): 9-11 |
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| 作者姓名： | 李美平 何承敏 胡继鹰 尤行宏 胡平 |
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| 作者单位： | 湖北中医药大学; |
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| 基金项目： | 湖北省教育厅重点课题(2001A04012) |
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| 摘 要： | 目的 观察甘草汤对大鼠心肌缺血再灌注损伤的影响,并探讨其机制.方法 采用结扎左冠状动脉前降支15rain,再灌注30rain后制备大鼠心肌缺血再灌注模型.以再灌性心律失常、血清NO含量和心肌Ca2+-Mg2+-ATPase活性为观察指标.结果 甘草汤组动物再灌注心律失常发生率低于模型组(P<0.01),血清N0含量显著...
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| 关 键 词： | 甘草汤 缺血再灌注损伤 一氧化氮 ATP酶 |
The Effects of Gancao Decoction on Myocardial Ischemia Reperfusion Injury in ,Rats |
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| LI Meiping,HE Chengmin,HU Jiying,YOU Xinghong,HU Ping. The Effects of Gancao Decoction on Myocardial Ischemia Reperfusion Injury in ,Rats[J]. Journal of Hubei University of Chinese Medicine, 2011, 13(1): 9-11 |
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| Authors: | LI Meiping HE Chengmin HU Jiying YOU Xinghong HU Ping |
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| Affiliation: | LI Meiping,HE Chengmin,HU Jiying,YOU Xinghong,HU Ping(Hubei University of Traditional Chinese Medicine,Wuhan 430065,Hubei) |
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| Abstract: | Objective To observe The effects of Gancao decoction on myocardial ischemia-reperfusion injury in rats and its mechanism.Methods Myocardial ischemia-reperfusion injury model was induced by ligation of the left anterior descending coronary artery 15min followed by 30min reperfusion.All the indexes(reperfusion arrhythmia,serum NO and myocardial Ca2+-Mg2+-ATPase activity) were measured.Results Compared with model group,the incidence of reperfusion arrhythmias of Gancao decoction group was obviously decreased(P... |
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| Keywords: | Gancao decoction Ischemia-reperfusion injury Nitric oxide ATP enzyme |
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