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Effects of edaravone on reperfusion injury in patients with acute myocardial infarction |
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| Authors: | Tsujita Kenichi Shimomura Hideki Kawano Hiroaki Hokamaki Jun Fukuda Masaya Yamashita Takuro Hida Satoru Nakamura Yoshinori Nagayoshi Yasuhiro Sakamoto Tomohiro Yoshimura Michihiro Arai Hidekazu Ogawa Hisao |
| Affiliation: | Department of Cardiology, Fukuoka Tokushukai Medical Center, 4-5 Sugu-kita, Kasuga City, Fukuoka 816-0864, Japan. |
| Abstract: | This clinical pilot study was a randomized, controlled, open-label study in 80 patients with acute myocardial infarction and was designed to examine the effects of a novel free radical scavenger, edaravone. Administration of edaravone before myocardial reperfusion was associated with smaller enzymatic infarcts and better clinical outcome. |
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