| 桑寄生对去卵巢骨质疏松大鼠的影响 |
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| 引用本文： | 武贵红. 桑寄生对去卵巢骨质疏松大鼠的影响[J]. 长治医学院学报, 2009, 23(6): 408-409 |
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| 作者姓名： | 武贵红 |
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| 作者单位： | 长治市卫生局合医办,046011 |
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| 摘 要： | 目的:观察桑寄生对去卵巢大鼠骨质疏松影响,并探讨其作用机制.方法:将26只Wistar大鼠随机分为假手术组(8只)、模型组(8只)、桑寄生组(10只).模型组和桑寄生组切除大鼠双侧卵巢, 制备去卵巢骨质疏松的动物模型,观察服用桑寄生水煎剂后,去卵巢骨质疏松大鼠骨密度(BMD)、血清雌二醇( E2 )、骨钙素(BGP)及抗酒石酸酸性磷酸酶(TRACP)的变化.结果:模型组大鼠的E2和BMD水平显著下降(P<0.01),而血清BGP和TRACP水平明显升高(P<0.01).桑寄生组大鼠BMD水平增加,而 TRACP水平得到恢复.结论:桑寄生能抑制去卵巢大鼠的骨质疏松,具有调节骨代谢的作用.
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| 关 键 词： | 桑寄生 骨质疏松 雌激素 骨钙素 |
Effects of HERBA TAXILLI on Ovariectomized Osteoporotic Rats |
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| Wu Guihong. Effects of HERBA TAXILLI on Ovariectomized Osteoporotic Rats[J]. Journal of Changzhi Medical College, 2009, 23(6): 408-409 |
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| Authors: | Wu Guihong |
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| Abstract: | Objective:Observe the effect of the HERBA TAXILLI on osteoporosis in ovariectomy rat and primarily research its mechanism.Methods:Twenty-six Wistar rats were randomly divided into three groups :SHAM,OVX and OVX + HT group.Rats in OVX and OVX+HT group was ablated bilateral ovarian.Wistar rats were drunken and its effects on osteoporosis were observed.Its blood was collected to assay estrogen(E2),bone gla protein(BGP),TRACP levels.The bone densities of the femur were measured.Results:Rats in OVX group display... |
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| Keywords: | HERBA TAXILLI Osteoporosis Estrogen BGP |
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