子宫内膜异位症复发的相关因素研究

目的:分析子宫内膜异位症复发的相关因素。方法:选择2008年1月～2010年12月在吉林大学第二医院妇产科手术治疗的子宫内膜异位症术后2年内复发的患者60例,采用单因素与多因素Logistic回归分析方法,分析可能影响患者术后复发的相关因素。结果:经单因素与多因素Logistic回归分析,子宫内膜异位症患者的痛经史、手术分期、后穹窿触痛结节、术后药物治疗、盆腔炎、子宫腺肌病和术后孕次等7个临床指标均与术后复发密切相关(P<0.05)。结论:子宫内膜异位症患者行手术治疗时,应根据其痛经史、手术分期、后穹窿触痛结节、术后药物治疗、盆腔炎、子宫腺肌病和是否有生育要求等选用创伤小、能彻底清除病灶的个体化治疗方案,术后短期应用抑制卵巢功能的药物可以减少复发。

Study on related factors of recurrence of endometriosis

Objective:To analyze the related factors of recurrence of endometriosis.Methods:Sixty patients were diagnosed as endometriosis and underwent surgerical therapy in department of gynecology and obstetrics,the Second Sffiliated Hospital of Jilin University from Janaury 2008 to December 2010,and then they were found recurrence within two years after surgery,the sixty patients were selected as research objects in the study;univariate logistic regression analysis and multivariate logistic regression analysis were performed in the study to analyze the related factors which may affect postoperative recurrence.Results:Univariate logistic regression analysis and multivariate logistic regression analysis were performed in the study,then the results showed that seven clinical indexes of patients with endometriosis were closely correlated with postoperative recurrence,there was statistically significant difference(P<0.05),the seven clinical indexes were listed as follows: the history of dysmenorrhea,surgical stages,painful nodules in uterine posterior fornix,postoperative drug thearpy,pelvic inflammatory disease,adenomyosis,and postoperative gravidity.Conclusion:For patients with endometriosis,when conducting surgical therapy,an individulized therapeutic regimen of minimal invasion and cleaning foci comletely should be adopted according to the history of dysmenorrhea,surgical stages,painful nodules in uterine posterior fornix,postoperative drug thearpy,pelvic inflammatory disease,adenomyosis,and having birth demand or not,applying drugs inhibiting ovarian function for a short time after surgery can reduce recurrence.