肌壁大部切除-子宫重建术联合曼月乐治疗中、重度子宫腺肌病的疗效

目的:观察肌壁大部切除子宫重建术(MURU)联合曼月乐(LNG-IUS,IUS)治疗中、重度子宫腺肌病(AMS)的近期效果。方法:观察分析45例行MURU+IUS治疗的中、重度AMS患者术前和术后3个月的痛经、经量、子宫体积、CA125以及IUS位置。结果:术前患者痛经评分、经量评分、CA125、子宫体积分别为:(6.31±3.33)分、(4.15±0.44)分、(76.51±44.62)U/ml、(273.73±109.69)cm3,术后3个月以上指标分别为:0.00分、(0.70±0.60)分、(10.12±4.03)U/ml、(58.80±23.17)cm3(P<0.01);IUS无脱落、嵌顿或异位发生。结论:MURU联合IUS治疗中、重度AMS的近期疗效非常显著,无并发症发生,值得进一步观察研究。

Curative effect of major uterine wall resection and uterine reconstruction combined with mirena for treatment of moderate to severe adenomyosis

Objective:To observe the short-term effect of major uterine wall resection and uterine reconstruction combined with mirena for treatment of moderate to severe adenomyosis.Methods:Dysmenorrhea,menstrual blood volume,uterine volume,CA125 level,and location of minera of 45 patients with moderate to severe adenomyosis treated with major uterine wall resection and uterine reconstruction combined with mirena before surgery and at three months after surgery were observed and analyzed.Results:The scores of dysmenorrhea and menstrual blood volume,CA125 level,and uterine volume before treatment were(6.31±3.33),(4.15±0.44),(76.51±44.62) U/ml,and(273.73±109.69) cm3,respectively.At 3 months after treatment,the above-mentioned indexes were 0.00,(0.70±0.60),(10.12±4.03) U/ml,and(58.80±23.17) cm3,respectively,there was statistically significant difference(P<0.01).No shedding,incarceration or ectopia of minera were observed.Conclusion:The short-termm effect of major uterine wall resection and uterine reconstruction combined with mirena for treatment of moderate to severe adenomyosis was significant,no complications were found.The method is worthy to be further observed and researched.