血清总胆汁酸、前白蛋白及乳酸脱氢酶在病毒性肝炎的变化及其临床意义

目的 :探讨总胆汁酸 (TBA)、前白蛋白 (PA )及乳酸脱氢酶 (L DH)在病毒性肝炎的变化及其临床意义。方法 :对 136例各型病毒性肝炎进行 TBA、PA及 L DH测定 ,其中急性肝炎 10 0例 ,重症型肝炎 12例 ,慢性活动型肝炎 8例 ,慢性迁延型肝炎 16例 ,与正常对照组比较经统计学分析处理。结果 :各组与对照组的水平间差异有显著性。尤以重症型肝炎、急性肝炎、慢性活动型肝炎较为明显 (P<0 .0 1) ,慢性迁延型肝炎次之 (P<0 .0 5 )。结论 :TBA测定可作为了解肝细胞损害程度上的一个敏感指标 ,可作为划分慢性活动型肝炎与慢性迁延型肝炎的重要指标。PA、L DH能真实反映各型肝炎早期细胞损害程度 ,对临床病毒性肝炎的早期诊断和治疗监测有重要意义。

A Chang Clinical Significance of Surum Total Bile Acid Proalbumin and LDH in Viral Hepatits

Objective To investigate the change clinical significance of surum total bile acid prealbumin and LDH in viral Hepatitis.Methods the 136 cases of viral hepatitis were examined in serum Total Bile Acid (TBA),Prealbumin (PA) and Lactic Acid Dehydrogenase ( LDH),including 100 cases of acute hepatitis, 12 cases of severe hepatitis,8 cases of chronic active hepatitis(CAH),and 16 cases of chronic organizing hepatitis (COH), comparing with the normal control and ananlysed by statistics.Results There are the significance differentiae between each group and the control, especiallyinsevere hepatitis (P<0.01) and CHO (P<0.05).Conclusions Examining TBA is a sensitive index as to find out the degree of hepatitis cell injury,and as an important index to differentiaste CAH and COH PA and LDH canreally reflect the level of eaely diagnosis and treatment monitoring in viral hepatitis.