| 经导管肝动脉化疗栓塞术对原发性肝癌患者细胞免疫及调节T细胞的影响 |
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| 引用本文： | 廖娟,王春晖,李肖,孟文彤. 经导管肝动脉化疗栓塞术对原发性肝癌患者细胞免疫及调节T细胞的影响[J]. 肝脏, 2011, 16(3): 198-201 |
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| 作者姓名： | 廖娟 王春晖 李肖 孟文彤 |
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| 作者单位： | 1. 四川大学华西医院消化内科,成都,610041
2. 四川大学华西医院血液研究室,成都,610041 |
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| 基金项目： | 四川省青年科技基金资助项目 |
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| 摘 要： | 目的 探讨原发性肝癌(PLC)患者经导管肝动脉化疗栓塞术(TACE)前后细胞免疫及调节T细胞(Treg)的变化及其临床价值.方法 采用流式细胞术检测健康志愿者及PLC患者介入治疗术前1 d与术后1个月外周血CD4+、CD8+T细胞及调节T细胞的比例变化;ELISA法检测外周血IL-35的含量.结果 PLC患者外周血中C...
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| 关 键 词： | 原发性肝癌 经导管肝动脉化疗栓塞术 免疫调节细胞 IL-35 甲胎蛋白 |
Effect of TACE on cellular immune function and Treg in patients with primary liver cancer (PLC) |
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| LIAO Juan,WANG Chun-hui,LI Xiao,MENG Wen-tong. Effect of TACE on cellular immune function and Treg in patients with primary liver cancer (PLC)[J]. Chinese Hepatology, 2011, 16(3): 198-201 |
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| Authors: | LIAO Juan WANG Chun-hui LI Xiao MENG Wen-tong |
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| Affiliation: | LIAO Juan,WANG Chun-hui,LI Xiao,MENG Wen-tong.Department of Gastroenterology,West China Hospital of Sichuan University.Chengdu 610041,China |
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| Abstract: | Objective To investigate the changes of cellular immune function and CD4+CD25+ regulatory T cells(Treg) in peripheral blood of patients with primary liver cancer(PLC) before and after transcatheter arterial chemoembolization(TACE) and their clinical implications.Methods The proportion of CD4+CD25+ Treg among CD4+ T lymphocytes and the proportion of CD4+ and CD8+ T cells of PBMC in peripheral blood of 35 patients with PLC were detected by flow cytometry 1 day before and 1 month after TACE.The level of IL-35 ... |
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| Keywords: | IL-35 |
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